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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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Most Cited

CITATIONS REPORT: (Source- Google Scholar)
 
Year 202020212022Total
No. of Published Articles 745760548 2053
Citations 69926321 983
Projected Impact Factor 3.7620.64  
Total Citations: 48275
 
Title
Views
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Cited
16.

DEVELOPMENT AND VALIDATION OF SIMPLE EFFECTIVE HPLC METHOD FOR THE QUANTITATIVE DETERMINATION OF RELATED SUBSTANCE PRESENT IN SITAGLIPTIN PHOSPHATE DRUG SUBSTANCE

An efficient and sensitive RPHPLC method was developed and validated for the estimation of Sitagliptin Phosphate process impurities in drug substances which were identified and characterized by LCMS, FTIR, 1H NMR, C NMR techniques. The method was carried out on a Symmetry shield RP 18 column at 25°C using a 1 % Perchloric acid and acetonitrile in gradient mode of pump. The flow rate is 1.2 ml/min...

Meher Vijay Dalawai *, Paul Douglas Sanasi and Hemant Kumar Sharma

Aurobindo Pharma Limited Research Centre-II, Indrakaran village, Sangareddy Mandal, Medak district, Andhra Pradesh, India

DOI: 10.13040/IJPSR.0975-8232.7(4).1493-02

1493-02

6134

1905

17.

DOSE OPTIMIZATION OF CEFTRIAXONE-SULBACTAM COMBINATION IN PEDIATRIC USING IN-VITRO SYSTEMS AND STOCHASTIC SIMULATIONS APPROACHES

Increase in complexity and cost associated with pediatric safety and efficacy studies have reduced the interest of pharmaceutical companies to study bio-therapeutics in pediatric population. Dose recommendations are being made as per patient body weight or body surface area, with the assumption of linearity in body size dose adjustments. In the present study, newer approach i.e. flat fixed age-bas...

Vishnu Dutt Sharma, Aman Singla, Manu Chaudhary and Manish Taneja*

Venus Medicine Research Centre, Hill Top Estate, Bhatoli Kalan, H.P., India.

DOI: 10.13040/IJPSR.0975-8232.7(4).1503-12

1503-12

16390

1608

25.

A NOVEL ASSAY METHOD OF 1-DEOXY NOJIRIMYCINE (DNJ) BY ION CHROMATOGRAPHY

A novel Assay method for the determinationof1-Deoxy nojirimycine(DNJ) was proposed by the authors using ion chromatography. The method was found to be accurate, simple and precise. A method precision RSD of 0.5%, RSD for intermediate precision of 0.6% and correlation coefficient was found to be 0.9999. A recovery of 99.7 to 100.1% at 50%, 100% and 150% levels was found. The DNJ solutions and mobil...

Nagaraju Rajana*, Rubia Lasker, Venkatesh P, Kaviraj Yarbagi, Balakumaran K and J. Moses Babu

Analytical Research, Custom Pharmaceutical Services, Dr. Reddy’s Laboratories Ltd., Bollaram road, Miyapur, Hyderabad (TS), India.

DOI: 10.13040/IJPSR.0975-8232.7(4).1580-89

1580-89

4726

2181

27.

ANTICANCER ACTIVITY OF AN ETHANOL EXTRACT OF COLEUS FORSKOHLII ROOT AGAINST GASTRIC CANCER CELLS IN-VITRO

Coleus forskohlii is an Indian medicinal plant it treat various diseases of cardiovascular, respiratory, gastrointestinal, and central nervous systems. The purpose of this study was to investigate the anticancer activity of an ethanol extract of Coleus forskohlii against gastric cancer in AGS cancer cell lines. Gastric carcinoma cells were tested in vitro for cytotoxicity, Ao/EtBr staining for apo...

Krishnamoorthy Rajkumar and Ramaswamy Malathi *

PG and Research Department of Biotechnology , Sri Vinayaga College of Arts and Science, Ulundurpet, Tamilnadu, India

DOI: 10.13040/IJPSR.0975-8232.7(4).1603-11

1603-11

3832

1423

33.

STUDY OF THE BINDING PROPERTIES OF GUM OBTAINED FROM CURCUMA AMADA ON MODEL DRUG PARACETAMOL

The aim of the present study is to evaluate the gum of Curcuma amada (mango ginger) as a tablet binder employing paracetamol as a model drug. Natural gums are economic, easily available and found useful as tablet binder. The physicochemical properties of a gum obtained from the rhizomes of Curcuma amada were characterized by Fourier transmittance infra red (FTIR) and Differential scanning colorime...

N. Thakur *, P. Mittal, M. Goswami, R. Kaur, R. Bansal, M. Bansal, and V. Gupta

Chandigarh University, Gharuan, Mohali, Punjab, India

DOI: 10.13040/IJPSR.0975-8232.7(4).1645-55

1645-55

3579

1244

41.

CHEMICAL ANALYSIS OF THREE SAUDI MEDICINAL PLANTS AND THEIR ANTIBACTERIAL ACTIVITY AGAINST MULTI-DRUG RESISTANT BACTERIA

The present work aims to examine the antimicrobial activity of three medicinal plant extracts grown in Saudi Arabia namely Pulicaria crispa, Achillea fragrantissima and Cleome Africana against 10 clinical isolates of multi-drug resistant bacteria (MDR) that belong to four species, Staphylococcus aureus, Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumonia. The antibacterial pot...

Leena Zino , Abdulnaser Alsharaa *, Sahar Al-Dossary , Afnan Alwadey and Basheer Chanbasha

Department of Chemistry, King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia.

DOI: 10.13040/IJPSR.0975-8232.7(4).1710-15

1710-15

3774

1152

42.

EVALUATION OF THE ANTIMICROBIAL, ANALGESIC AND ANTIOXIDANT ACTIVITY OF ETHANOLIC EXTRACT OF THE LEAVES OF AVERRHOA CARAMBOLA

Aim: Evaluation of the antimicrobial, analgesic and antioxidant activity of ethanolic extract of the leaves of Averrhoa Carambola. Materials and methods: To test the antimicrobial activity the organisms used were S. aureus, Klebsiella sp, E. coli and P. aeruginosa, C. albicans. Zone of inhibitions produced by sensitive organisms were demarcated by a circular area of clearing around plant extract i...

Swopna Phukan and Atifa Ahmed

Department of Pharmacology, Gauhati Medical College and Hospital, Guwahati, Assam, India

DOI: 10.13040/IJPSR.0975-8232.7(4).1716-23

1716-23

5240

1529

45.

FORMULATION, OPTIMIZATION & EVALUATION OF SOLID DISPERSION BASED GASTRORETENTIVE FLOATING TABLETS OF CEFPODOXIME PROXETIL

The objective of present study was to preclude of poor dissolution of relatively water insoluble and poorly permeable drug by formulating gastroretentive floating tablet using solid dispersion (SD) of the drug. It aimed to increase the drug solubility and gastric retention of the drug for better absorption profile. Cefpodoxime proxetil is an orally absorbed third generation cephalosporin antibioti...

Nidhi Saini*, Rakesh Kumar, Manju Yadav and Kamal Saroha

Institute of Pharmaceutical Sciencies, Kurukshetra University Kurukshetra, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.7(4).1734-39

1734-39

4411

1352

21.

RP-LC METHOD DEVELOPED FOR THE DETERMINATION OF ASCORBIC ACID IN VITAMIN C SYRUP PREPARATION

Ascorbic acid is one of the essential and most vital medicines needed to maintain healthy living. Due to its non-availability through endogenous biosynthesis in humans, it is arguably one of the most consumed Over-The-Counter drugs. Thus, a simple, precise, low-cost and accurate reversed-phase liquid chromatographic (RP-LC) method was developed and optimized to analyse for the percentage content o...

K. B. Mustapha *, A. A. Kelong, T. A. Adelakun, A. A. Theophilus and O. O. Obodozie-Ofoegbu

Department of Medicinal Chemistry and Quality Control 1, National Institute for Pharmaceutical Research and Development, Idu, Abuja, Nigeria

DOI: 10.13040/IJPSR.0975-8232.7(5).2001-08

2001-08

5985

2071

28.

IN-VITRO ANTIMICROBIAL ACTIVITY OF CRUDE EXTRACT OF FICUS ARNOTTIANA MIQ. LEAVES (MORACEACE): AN ETHNOMEDICINAL PLANT

This study was carried out with an objective to investigate the antibacterial and antifungal potentials of leaves of Ficus arnottiana Miq. The aim of the study is to assess the antimicrobial activity and to determine the zone of inhibition of extracts on some bacterial and fungal strains. In the present study, the microbial activity of ethyl acetate, methanol and aqueous extracts of leaves of Ficu...

Gurpreet Kaur * and Satnam Singh

School of Pharmacy & Emerging Science, Baddi University of Emerging Sciences and Technology, Baddi (Solan) Himachal Pradesh, India

DOI: 10.13040/IJPSR.0975-8232.7(5).2057-64

2057-64

3590

1298