FORMULATION AND EVALUATION OF FAST DISSOLVING TABLETS OF GRANISETRON HYDROCHLORIDE BY DRY GRNULATION METHOD
The aim of work is to characterization and evaluation of fast dissolving tablet of Granisetron hydrochloride using three superdisintegrants like crosscarmellose sodium, crosspovidone and sodium starch glycolate. FTIR studies revealed that there was no physico-chemical interaction between granisetron hydrochloride and other excipients. The tablets were prepared by dry granulation method and all had...
ANTIDIABETIC EFFECT OF THE SAPONIN-RICH FRACTION OF THE EXTRACT OF TAMARINDUS INDICA L. ON EXPERIMENTAL HYPERGLYCAEMIA
It is estimated that more than 170 million people are suffering from diabetes globally and this number is expected to double by 2030, and the greatest increase in prevalence is, however, expected to occur in Asia and Africa. Diabetes is the most common endocrine disease and its prevalence is reaching epidemic proportion worldwide. Tamarindus indica is a slow growing tree that is resistant to stron...
This paper focuses on a favor in order to examine the implications of patents on innovation in the view of biotechnological developments and the utilization and associated efficacy of present patent system in promoting biotechnological innovations and the related issues and challenges therein. This article deals with patent related area in field of biotechnology. It discusses the various issues in...
Many infectious diseases are known to be treated with herbal remedies throughout the history of mankind. Even today, plant materials continue to play a major role in primary health care as therapeutic remedies in many developing countries. Traditional system of medicine is found to have utilities as many accounts. Due to population rise adequate supply of drug and high cost of treatment in side ef...
Background: Familial Hypercholesterolemia (FH) is an autosomal dominant disorder caused by mutation in the LDL receptor gene and characterized by raised LDL-C, tendon xanthomata and premature atherosclerosis. Existing therapies for FH such as statins and LDL apheresis do not offer adequate lipid control in most patients, which has led to the search for more definite alternatives. Two new drugs hav...
The objective of this review was to bring a chemicophysical approach towards dendrimers in different aspects including host-guest interaction and drug targeting. These nanosizedz polymeric molecules are unique in structural properties which have made dendrimers a potential candidate to lend itself as a carrier for drugs and bioactive molecules. Dendrimers offer the coupling of guest molecule...
The transition in diet has lead to an increase in lifestyle disorders and thereby increased dependency on wonder drugs. With increased drug discovery and marketing, there is a compelling trend towards large drug dosage. However, food is judged not only for its nutritive properties but also for its ability to improve the health and well being of consumers, thus leading to the advent of “FUNCTIONA...
Microbial fibrinolytic proteases are of considerable interest in view of their specific activity and stability at biological pH. This review describes different isolation methods which enable the screening and selection of promising organisms for industrial production. Further, strain improvement using mutagenesis and/or recombinant DNA technology can be applied to augment the efficiency of the pr...
Present study was designed to evaluate the antioxidant and hematoprotective activity of methanolic extract of saraca indica bark. Antioxidants and hematoprotective effect of saraca indica bark may be due to its polyphenolic compounds. Polyphenols act as reducing agents via scavenging of free radicals and chelation of transition metals. The hematoprotective activity of Saraca indica was studied in ...
STUDY OF TOTAL PHENOLICS, TOTAL TANNINS ANTIOXIDANT POTENTIAL AND ANTIMICROBIAL ACTIVITY OF AILANTHUS EXCELSA L
Ailanthus excelsa leaves were evaluated for antimicrobial activity against clinical isolates obtained from patients with eye and skin infections and also for its antioxidant potential. The bacterial isolates obtained were identified to be S. aureus, P. aeruginosa, E. coli and the fungal isolates were identified as Aspergillus niger and Penicillium. The extract showed a maximum zone of inhibition a...