Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 3.76 | 2 | 0.64 |
A COMPARATIVE STUDY OF THE IN VITRO ANTIBACTERIAL ACTIVITY OF ENDOCARP, DATE PALM TISSUE AND DATE PALM TISSUE WITH ENDOCARP TOGETHER AGAINST SOME GRAM NEGATIVE AND GRAM POSITIVE PATHOGENIC BACTERIA
The antibacterial activities of water extracts of the three major parts of the date palm fruit were compared against Eschereshia coli; Klebsiella pneumonia; Salmonella enteritidis; Pseudomonas aeruginosa; Staphylococcus aureus using the agar well diffusion method. Endocarp extract showed a wide range of activity against all Gram negative bacteria while it exhibited a low activity against Gram posi...
3239
1144
RECENT DEVELOPMENT AND ACHIEVEMENTS IN SOLUBILITY AND DISSOLUTION ENHANCEMENT OF ITRACONAZOLE: A REVIEW
A drug should be available in accessible in disintegrated state before producing its therapeutic effect however; in current market more than 40%, drugs are poorly soluble in water. In view of their low aqueous solubility, those new chemical entities fail to reach market in spite of revealing potential pharmacodynamics activities. Poorly aqueous soluble drugs are connected with moderate drug absor...
8403
2086
OPTIMIZATION AND VALIDATION OF A METHOD FOR THE QUANTIFICATION OF POLYSACCHARIDES OF THUJA OCCIDENTALIS LINN.
The anthrone method has been employed for many years in the spectrophotometric determination of polysaccharides. However, taking into account that its use usually involves a series of steps and requires a long period of analysis, this study aimed to conduct a more detailed assessment of its application in the determination of total polysaccharides from the aerial parts of Thuja occidentalis Linn. ...
3757
1500
IMPACT OF PROBIOTICS LACTOBACILLUS RHAMNOSUS AND LACTOBACILLUS CASEI ON LIPOGLYCEMIC AND ANTIOXIDATIVE STATUS OF DIABETIC RATS
Probiotics are live microorganisms, which when administered in adequate amounts confer a health benefit. There are very limited studies on antidiabetic effect of lactic acid bacteria despite their potentiality in reducing the risk of diabetes onset. The present study explored the effect of administering live culture of L. rhamnosus [MTCC No 8712] and L. casei [MTCC No 1408] in STZ induced diab...
3709
1318
VALIDATION OF A NOVEL RP-HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF AMLODIPINE BESYLATE AND NEBIVOLOL HYDROCHLORIDE IN BULK AND PHARMACEUTICAL DOSAGE FORMS
This experimental work present the development and validation of a simple, rapid, accurate and precise RP-HPLC method for the simultaneous estimation of amlodipine besylate (AMB) and nebivolol hydrochloride (NBH) in bulk drug and pharmaceutical dosage forms. The chromatographic separation was carried out with AGILENT 1120 liquid chromatograph in an isocratic mode using Kromasil ODS column (250 x 4...
2863
1101
SIGNIFICANCE OF CA 125 AND CEA AS BIOMARKERS IN ASSESSING PROGRESS OF TREATMENT FOR CERVICAL CANCER
Background: Cervical cancer (CC) is the second leading cause of cancer deaths in women, with more than 80% of these occurring in developing countries that have limited access to screening programs. Therefore there is a need to develop diagnostic and prognostic biomarkers which can be quantifiable and help clinical oncologists at the first interaction with the suspected patients. The aim of this st...
5813
1842
BIOACTIVE COMPOUNDS IDENTIFICATION FROM MARINE MACRO ALGAE PADINA AUSTRALIS USING METHANOL EXTRACT
The investigation was carried out to determine the possible bioactive compounds marine macro algae Padina australis using methanol extract. The GC-MS analysis of methanol extract was performed using perkin Elmer GC clarus. Six compounds were identified from Padina australis showed highest peak area Pentadecanoic acid 14-methyl ester [100%] followed by 1, 2 Benzenedi carboxylic acid, butyl octyl es...
3205
1399
SPECTROPHOTOMETRIC & RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF LEVOFLOXACIN & ORNIDAZOLE
An accurate, precise and reproducible UV-spectro-photometric methods and liquid chromatographic assay method were developed and validated for the determination of Levofloxacin and Ornidazole in tablet dosage form. Spectrophotometric estimation was done by simultaneous equation method and 50% methanol as solvent. In this method λmax for LEVO and OZ were selected at 293.5nm and 318nm. RP-HPLC analy...
4593
1338
STUDY OF PHYSIOCHEMICAL ANALYSIS OF ACHYRANTHES ASPERA EXTRACTS
Achyranthes aspera (Amaranthaceae) is an important medicinal herb found as a weed throughout India. It has been used in almost all the traditional system of medicine, ayurveda, unani, and sidha from the ancient time. It serves as a folk medicine in traditional uses. In present study, the methanolic extract and aqueous extracts of leaf, stem, inflorescence and roots of Achyranthes aspera was screen...
4679
1686
SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME NEW 1, 6- DIPHENYL-10, 10a-DIHYDROPYRIDO[2, 3-d]-1, 2, 4-TRIAZOLO [4, 3-a]PYRIMIDIN-5(1H)-ONE DERIVATIVES
In this research, a new series of total twenty derivatives (39-58) of titled compound were synthesized with the help of substituted acetophenone which undergoes Aldol condensation reaction with dimethyformamidedimethylacetal (DMFDMA) to form corresponding unsaturated carbonyl compounds such as enaminones. The compound 2-thioxo-1,3-dihydropyridino[2,3-d] pyrimidin-4(1H)-one were obtained by reactin...
3224
1990