Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 3.76 | 2 | 0.64 |
PREPARATION AND CHARACTERIZATION OF CIPROFLOXACIN LOADED TRANSDERMAL PATCHES
The aim of this research was to formulate a matrix-type transdermal therapeutic system containing drug ciprofloxacin with different ratios of hydrophobic (ethyl cellulose) polymer by solvent evaporation technique, using 15% w/w of dibutyl phthalate to the polymer weight, incorporated as plasticizer. Different concentrations of isopropyl myristate were used to enhance the transdermal permeation of ...
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EXTRACTION AND PHYTOCHEMICAL SCREENING OF MIKANIA SCANDENS LINN. AND EVALUATION OF ITS METHANOLIC EXTRACT FOR ANALGESIC ACTIVITY
Mikania scandens is a rapidly growing herbaceous to semi-woody, perennial vine. It grows quickly over other plants such as young trees, smothering them; it can climb trees up to 25 m tall. Although not as serious a weed as M. chordate, in Southeast Asia it has become a hard to eradicate weed of tea, rubber, and other plantation crops. It also reduces the carrying capacity of pasture. The achenes a...
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INHIBITION OF ACETYLCHOLINESTERASE IN ALZHEIMER’S DISEASE- AN IN SILICO APPROACH
Alzheimer's disease (AD) is a progressive degenerative disease of the brain marked by gradual and irreversible declines in cognitive functions. Acetylcholinesterase plays a biological role in the termination of nerve impulse transmissions at cholinergic synapses by rapid hydrolysis of acetylcholine. The deficit levels of acetylcholine lead to poor nerve impulse transmission. Thus the cholinesteras...
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STUDY OF THE PROLONGED RELEASE OF A DRUG FROM ENCAPSULATED GRANULES PREPARED WITH BEESWAX
The in vitro dissolution studies of encapsulated sodium salicylate granules coated with beeswax is presented. The factors investigated were the effects of concentration, presence of a hydrophilic fatty material, polyethylene glycol 6000 (PEG 6000), and technique (pan-coating, fusion and granulation) on the sustained release of drug when coated with beeswax. Comparison of release rates was based on...
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ANTIDIABETIC ACTIVITY OF PARKINSONIA ACCULEATA LINN IN RABBITS, EMPHASIS ON C REACTIVE PROTIENS
Parkinsonia acculeata is used in traditional medicine for the treatment of jaundice and diabetes. Accordingly, the present study was designed to investigate the effects of Pet ether and aqueous extracts of the leaves of Parkinsonia acculeata on glucose homeostasis in alloxan induced diabetis in rabbits. After 7 days of study it showed that Parkinsonia acculeata reduced glucose levels significantly...
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BINDING TO AND RETENTION BY MUCOSAL CELLS OF THE TAMARINDUS INDICA SEED POLYSACCHARIDE: VISUAL EVALUATION BY MEANS OF INORGANIC AND ORGANIC MARKERS
The aim of this study was to investigate the possibility of using inorganic and organic markers to visualize the ability of the transparent polysaccharide (TSP) polymer isolated from the endosperm of the seed kernel of Tamarindus indica, a tree that mainly grows in India and South-East Asia, to bind to human mucosal cells. A layer of human buccal cells was prepared on slides and overlaid by 0.2 ml...
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EFFICIENT FORMULATION AND CHARACTERIZATION OF FLURBIPROFEN TRANSDERMAL GEL USING WATER SOLUBLE POLYACRYLAMIDE POLYMER
High molecular weights water soluble homopolymer type of acrylamide was reported to obtain very high viscosity in low concentration, transparency, film forming properties and useful in formation of transdermal gel. The flurbiprofen gels were prepared by using different concentration of polyacrylamide for topical drug delivery with an aim to gradually increase transparency and spreadability. Thes...
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TRITERPENE ACIDS FROM n-HEHANE EXTRACT 0F ALBIZZIA LEBBECK BENTH.
Two triterpine acids like 2α, 19α- dihydroxy – 3-oxo-12- ursen- 28-oic acid (1), 2α, 16α, 19α- trihydroxy – 3-oxo-12- ursen- 28-oic acid (2) were isolated from the n-hexane soluble fractions of a methanol extract of the root of Albizzia lebbeck Benth. The structures of the isolated compounds were elucidated as by extensive spectroscopic studies, including high field NMR analyses. This i...
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PHYSICOCHEMICAL CHARACTERIZATION AND QUANTIFICATION OF TOTAL ANTHRAQUINONES OF VISMIA GUIANENSIS (AUBL.) CHOISY
Vismia guianensis is a plant species of high occurrence in the Amazon and northeastern Brazil, which has been studied lately, because of its antimicrobial and anticancer properties.In order to make an herbal medicine, National Agency for Sanitary Surveillance of Brazil, recommends the production of a drug and plant extracts analysis report indicating: method, specifications and results obtained. T...
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INFLUENCE OF RIPENING ON ANTIOXIDANT ACTIVITY OF CELL WALL POLYSACCHARIDES IN PRUNUS ARMANIACA LINN.
Cell wall polysaccharides have been of great importance to society and mankind over the years. In the present study Cell wall polysaccharides were extracted from different stages viz- Immature green, mature green and ripe stages of Prunus armaniaca Linn. A decrease in the yield of pectin was observed during ripening.The pectin Extracted from various stages of fruit ripening was further analysed fo...
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