Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 3.76 | 2 | 0.64 |
FORMULATION DESIGN, IN-VITRO AND BIOLOGICAL CORRELATION OF SITE SPECIFIC DRUG DELIVERY SYSTEM FOR DISTAL GASTRO-INTESTINAL TRACT
The present study was designed to evaluate oral compression coated tablet formulation to achieve time and site specific drug release system to target lower GIT. A pectin based compression coated tablet formulation of different ratios and concentration of ethyl cellulose and cellulose acetate phthalate were designed and evaluated physico chemical parameters and for tinidazole release, compression c...
4021
1535
EFFECT OF ACAMPROSATE IN EXPERIMENTAL MODELS OF PERIPHERAL NEUROPATHIC AND INFLAMMATORY PAIN IN WISTAR RATS
Neuropathic pain is a persistent chronic pain caused by primary lesion or dysfunction of neurons which is primarily characterized by hyperalgesia, allodynia. There is some evidence that acamprosate might inhibit Ca2 influx through NMDA and voltage-dependent Ca2 channels. λ-carrageenan (0.1 ml of 1% w/v) into i.pl. region of the hind paw was injected to produce acute inflammation. Unilateral perip...
3827
1261
FORMULATION DESIGN, IN-VITRO AND BIOLOGICAL CORRELATION OF SITE SPECIFIC DRUG DELIVERY SYSTEM FOR DISTAL GASTRO-INTESTINAL TRACT
In the present studies was designed to evaluate oral compression coated tablet formulation to achieve time and site specific drug release system to target lower GIT. A pectin based compression coated tablet formulation of different ratios and concentration of ethyl cellulose and cellulose acetate phthalate were designed and evaluated physico chemical parameters and for tinidazole release, compress...
2937
1179
QUANTIFICATION OF CHLORHEXIDINE GLUCONATE FROM MOUTH RINSE AND SKIN DISINFECTANT SOLUTIONS USING A VAIDATED CHROMATOGRAPHIC TECHNIQUE
The study presents a simple and rapid chromatographic technique for the estimation of chlorhexidine gluconate for mouth wash using a combination of phosphate buffer and acetonitrile as mobile phase. The separation was carried out on a stainless steel column 250mm × 4.5mm packed with octadecyle silane particles. The detection was carried out using a dual lambda absorbance detector at 254nm wavelen...
10880
1988
SEA BUCKTHORN (H. RHAMNOIDES L.) MEDIATED ACUTE HYPOXIC TOLERANCE IN THE SKELETAL MUSCLE OF RATS BY DIFFERENTIAL ACTIVATION OF ENERGY METABOLISM AND ENHANCED ANTIOXIDANTS
Exposure to hypobaric hypoxia differentially affects physical performance and survival amongst individuals. The present study was designed to investigate the role of metabolic enzymes, antioxidants and bioenergetics molecular markers in the differential hypoxic tolerance of animals exposed to acute hypobaric hypoxia and the effect of herbal supplementation in augmentation of hypoxia tolerance. Adu...
3079
1250
PARTIAL PURIFICATION AND ANTIOXIDANT ACTIVITIES OF METHANOL EXTRACTS OF ACORUS CALAMUS.
In vitro antioxidant activity test was carried out on partially purification of methanol extract of Acorus calamus. Partially purification was done to obtain ten fractions. Partial purification was carried out by using hexane: ethyl acetate solvent system. These fractions were studied for the polyphenolics and antioxidant activity. S6 –S9 fractions shows maximum radical scavenging activity, ...
3374
1536
ANTIMICROBIAL ACTIVITY OF UPAVISHA AND ITS CLINICAL CORRELATION WITH CONTEMPORARY SCIENCE: A REVIEW
In Ayurveda, there are less toxic herbal drugs known as upavisha. Upavisha are mostly use in various diseases with many therapeutically preparations. As per Ayurveda, Upavisha is group of less toxic drug. These drugs are either not having all ten gunas or they have less potent gunas. The properties of these drugs are to cure acute and chronic disease. These groups also have antimicrobial/ anti- in...
7175
2633
PREPARATION AND IN VITRO EVALUATION OF IN SITU GELLING GASTRORETENTIVE SALBUTAMOL SULFATE LIQUID FORMULATIONS
Salbutamol is a selective β2-adreno-receptor stimulant and is given four times daily in a dose of 2.4 mg orally to maintain therapeutic blood level. It is known to be absorbed in proximal parts of the small intestine. Prolonging gastric residence time is, therefore, beneficial to improve its bioavailability. Hence, seven in situ gelling liquid formulations were prepared using sodium alginate (SA)...
4682
2073
SYNTHESIS OF HETEROCYCLIC NITROGEN COMPOUNDS BY CLOSURE REACTIONS USING TETRAACETYLETHANE WITH VARIOUS PRIMARY AMINES
This work includes synthesis of new five, six, and seven-heterocyclic nitrogen compounds by closure reactions of tetraacetylethane (3) with primary amines in refluxing ethanol and acetonitrile as solvents and without using any catalysts. The tetraacetylethane melting point 184-189 ºC was prepared by condensation of two anhydrous molecules of sodium salt of acetylacetone and in the presence of dry...
4689
1809
FORMULATION AND EVALUATION OF AQUEOUS EXTRACT OF GARLIC (ALLIUM SATIVUM) AS A PESSARY
A pessary is a type of suppository that is meant to be inserted into the vagina for treatment of local or systemic diseases, in folk medicine garlic bulb is inserted into vagina for treatment of candidiasis. The aim of this work is to formulate and evaluate aqueous extract of garlic as a pessary. Aqueous garlic (Allium sativum) extract was obtained from the garlic bulbs. The pessary was formulated...
3938
2449