Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 3.76 | 2 | 0.64 |
THE ICH GUIDELINES IN PRACTICE: FORCED DEGRADATION STUDIES OF DORIPENEM BY AN LC-MS COMPATIBLE RP-HPLC METHOD
In this manuscript, a fast, stability-indicating RP-HPLC method with UV detection was developed and validated to quantify doripenem in the bulk drug and its injectable formulation. The analysis was performed using Phenomenex (250 x 4.6mm, 5µm) ODS column with a flow rate of 1 mL min–1 and a SPD 20 A UV detector to monitor the eluate at 316 nm. The mobile phase was acetonitrile and 10 mM ammoniu...
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A CROSS-SECTIONAL STUDY ON SELF-MEDICATION FOR COVID-19 AND ASSOCIATED FACTORS AMONG ADULTS IN A RESIDENTIAL COLONY OF EAST DELHI
A cross-sectional study was conducted among 140 study subjects in an urban residential area of East Delhi selected by simple random sampling method to assess the prevalence of self-medication for Covid-19 and associated socio-demographic and economic factors. Data were collected by interviewing the study subjects using a pre-tested semi-structured interview schedule. The Mean+SD age of the study s...
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EFFECT OF SOLVENT SYSTEMS AND EXTRACTION TECHNIQUES ON TOTAL PHENOL, TOTAL FLAVONOID CONTENT AND ANTIOXIDANT ACTIVITY OF A POTENTIAL MEDICINAL PLANT TINOSPORA SINENSIS (LOUR.) MERR.
Tinospora sinensis (Lour.) Merr. belongs to the family Menispermaceae is, an important medicinal plant. Ayurveda, an Indian medicinal system, strongly advocates use of T. sinensis as a rejuvenator and several other therapeutic activities. The study's objectives were to assess the effect of the extraction procedure and different solvent systems on antioxidant, total phenol content and total flavono...
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SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL TETRAZOLE ANALOGUES OF FLAVONES AS ANTIMICROBIAL AGENTS
A series of flavones derivatives 11(a-j) have been synthesized and evaluated for their in-vitro antibacterial and antifungal activities. The antibacterial screening data showed that compounds with 4-methoxyphenyl (11c), 4-fluorophenyl (11d), and 2, 5-fluorophenyl (11h) substituent’s on tetrazole ring, showed the maximum activity against the organisms used. The antifungal screening revealed that ...
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METHOD DEVELOPMENT, VALIDATION AND FORCED DEGRADATION STUDIES OF NEW RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF REMOGLIFLOZIN AND TENELIGLIPTIN IN PURE AND TABLET DOSAGE FORM
According to ICH guidelines, an easy, cost-effective, accurate, and precise RP-HPLC method for simultaneously determining Remogliflzin and Teneligliptin was developed and validated. The drug's quantity was determined using a photodiode array (PDA) detector. The column was run in isocratic mode with mobile phase acetonitrile and ammonium phosphate buffer at a 40:60 ratio. The flow rate was one mill...
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A DOUBLE-BLINDED RANDOMIZED CONTROLLED STUDY IN PATIENTS UNDERGOING FOREARM AND HAND SURGERIES TO STUDY THE EFFECT OF LOW DOSE DEXAMETHASONE AS AN ADJUVANT TO ROPIVACAINE IN AXILLARY BRACHIAL PLEXUS BLOCK”
Introduction: Ultrasound-guided axillary brachial plexus block is commonly used for forearm and hand surgery. Perineural dexamethasone 8mg has proved to prolong the duration of analgesia, but studies with low doses of dexamethasone are scarce. Hence this study was designed to determine the duration of analgesia with 2 mg dexamethasone used perineurally with ropivacaine. Methods: Fifty-Eight patien...
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DISCRIMINATING DERIVATIVE SPECTROPHOTOMETRIC CONCURRENT QUANTIFICATION OF LORATADINE AND AMBROXOL IN TABLET DOSAGE FORM
Understanding the preponderance of respiratory conditions with the symptoms like sore throat and cough being even more common, owing to the coronavirus outbreak. The improved resolution method was developed to quantify drugs Loratidine and Ambroxol from the most effective dosage regimen to treat sore throat and cough. An accurate, precise method was developed for concurrently estimating drugs from...
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FORMULATION AND IN-VITRO EVALUATION OF ANTI-AGING FACE CREAM CONTAINING LACTIC ACID AND COCOA BUTTER
The main aim of the current research is to formulate and evaluate the anti-aging cream containing lactic acid and cocoa butter. Skin health and beauty is regarded as one of the most important variables influencing general "well-being" and "health" perception in humans because of that, various anti-aging techniques have been created in recent years. Uneven pigmentation, increased wrinkles, loss of ...
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ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY OF RED OCHRE TRITURATED WITH PUNICA GRANATUM (DADIM BHAVIT GAIRIKVATI)
Antibiotic or antifungal drug resistance is a major challenge in this era. Because the discovery and development of new drugs takes a long time. So, ancient medicine formulations are being checked for antimicrobial properties. Red ochre triturated with Punica granatum (Dadim bhavit gairikvati) is herbo-mineral formulation prepared by red ochre (Gairika/Ferric Oxide fe2O3) triturated with Punica g...
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FORMULATION AND EVALUATION OF DRY POWDER SUSPENSION USING HERBAL SEED EXTRACT
Introduction: Herbs, which have been used to cure numerous ailments since ancient times, are important in building the foundation of modern medications. They are relatively safe to use, easily available, and also affordable. The present study aimed to investigate dry powder suspension formulated with Linum usitatissimum seeds extract, Cucurbita pepo seeds extract, Sesamum indicum seeds extract and...
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