Most Popular
FORMULATION AND EVALUATION OF TRANSDERMAL PATCH OF PREGABALIN
The objective of present study is to determine the permeation of Pregabalin from transdermal patch into microcirculation of skin. Matrix type transdermal drug delivery system (TDDS) of Pregabalin was prepared by the solvent evaporation technique. Several batches were prepared by using combination of HPMC and PVP; PVA and PVP; Eudragit RL-100 and Eudragit RS-100; HPMC and EC in different ratios. Pr...
22180
3771
BIOLOGICAL AND MEDICINAL SIGNIFICANCE OF PYRIMIDINES: A REVIEW
Pyrimidine is a 5-membered heterocyclic ring which is versatile lead compound for designing potent bioactive agents. This interesting group of compound has diverse biological activities such as antimicrobial, CNS depressant, anti-inflammatory, analgesic, anti-convulsant, anticancer, antihelmentic, antioxidant and herbicidal. Available data represents that pyrimidine being heterocyclic planar five ...
22141
2576
DISINFECTANTS, REGULATION AND REQUIREMENTS – GLOBAL OVERVIEW
Surface disinfectant is the multi-billion-dollar global industry with continuous growth opportunities linked to advancements in technology and innovations. However, innovations and new advancements do not always reach consumers due to the lack of clarity related to the approval process of such innovations and stringent regulations by national health authorities. These regulations can pose challeng...
21814
2997
STABILITY INDICATING HPLC METHOD DEVELOPMENT: A REVIEW
High performance liquid chromatography is one of the most accurate methods widely used for the quantitative as well as qualitative analysis of drug product and is used for determining drug product stability. Stability indicating HPLC methods are used to separate various drug related impurities that are formed during the synthesis or manufacture of drug product. This article discusses the strategie...
21734
3847
FORMULATION AND EVALUATION OF METRONIDAZOLE EFFERVESCENT GRANULES
Efferevescent granules are granular dosage form of drug in a dry mixture usually composed of effervescents like sodium bicarbonate, citric acid and tartaric acid. Effervescent granules when added to water, the acids and the base react to liberate CO2, resulting in effervescence. A combination of tartaric acid and citric acid is used as an effervescent base rather than either acid alone because whe...
21704
2596
GLYCYRRHIZA GLABRA: A PHYTOPHARMACOLOGICAL REVIEW
Plants have been one of the important sources of medicines since the beginning of human cultivation. There is a growing demand for plant based medicines, health products, pharmaceuticals, food supplements, cosmetics etc. A review of chemical constituents present in various parts of Glycyrrhiza glabra and their pharmacological actions is given in the present article. Glycyrrhiza glabra Linn, is a c...
21621
6220
IN-VITRO EVALUATION OF TWO MARKETED BRANDS OF PARACETAMOL TABLETS USING QUALITY CONTROL TESTS
Paracetamol is a widely used non-prescription analgesic and antipyretic medicine. The study was conducted to assess the comparative in-vitro quality control parameters through the evaluation of weight variation, hardness, friability, disintegration time and dissolution profile between the commercially available tablet brands of paracetamol. Tablets of two manufacturers of the formulation were eval...
21612
3524
A COMPREHENSIVE REVIEW OF PLANTS USED AS CONTRACEPTIVES
Evaluation of herbs for anti-fertility effects has been in progress worldwide for several decades to identify effective and safe substances for control of population explosion. This population explosion will have negative impact on our economic policies and would simultaneously misbalance our socio-economic infrastructure. Family planning has been promoted through several methods of contraception,...
21588
3076
ASTAXANTHIN: A POTENTIAL CAROTENOID
Astaxanthin, a member of the carotenoid family, is a dark-red pigment which is the main carotenoid found in the marine world of algae and aquatic animals. Astaxanthin, is present in many types of seafood, including salmon, trout, red sea bream, shrimp and lobster, as well as in birds such as flamingo and quail. Synthetic Astaxanthin dominates the world market but recent interest in natural sources...
21573
2546
VARICOSE VEINS: AN OVERVIEW OF CURRENT AND HERBAL TREATMENTS
Varicose Veins can be explained as a disorder of the veins (especially of legs) wherein they get affected due to the backward flow and turbulence in the circulation of the blood. The veins get perverted, become enlarged due to a condition called edema. The disease also shows many associated symptoms which worsens the condition of the varicose veins. The present article deals with brief introductio...
21405
2643