Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 3.76 | 2 | 0.64 |
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF TRIMETAZIDINE BY EXTRACTIVE SPECTROPHOTOMETRY
Rapid, simple, sensitive and accurate spectrophotometric methods have been developed for the determination of Trimetazidine in pure and pharmaceutical formulations. Various methods were developed for estimation of trimetazidine .but a simple extractive photometric method using has not been developed .This method is based on the formation of chloroform soluble ion pair complex of Trimetazidine with...
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THEORETICAL STUDY OF THE ABSORPTION SPECTRA OF TRIAMTERENE
Time dependent density functional theory (TDDFT) calculations have been carried out to study the electronic structure and the UV absorption spectra of Triamterene. The UV spectra have been investigated with inclusion of solvent effect. The B3LYP functional with a 6-31G(d, p) basis sets have been used to compute absorption energies. The solvent effects have been described within the polarizable con...
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TARGETING ONCOGENIC KINASE SIGNALING WITH SMALL MOLECULE KINASE INHIBITOR IMATINIB
Protein tyrosine kinases (PTKs) are key players in cellular signal transduction events and have essential roles in cell growth, survival, differentiation and migration. Perturbations in protein tyrosine kinase activity have been implicated in a number of abnormalities, particularly cancer. Selective small molecule inhibitors are potential therapeutic agents targeting protein kinases involved in ca...
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IS EMERGENCY CONTRACEPTIVE ACCESSIBILITY A BARRIER IN DEVELOPING COUNTRIES? A REVIEW
Significant portion of maternal death in developing countries was attributed to induced abortions secondary to unwanted pregnancies. Using emergency contraception as a backup method can contribute to reduce unwanted pregnancy secondary to method failure, contraception non-use and also rape. The need for emergency contraception is clearly demonstrated by the occurrence of unwanted pregnancy and i...
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IMPACT OF VITAMINS IN PREVENTION OF RISK FACTORS ASSOCIATED WITH TYPE-2 DIABETES MELLITUS
Diabetes mellitus is one of the most common metabolic disorders that cause micro and macro vascular complications. Because of additive effects of hyperglycaemia and hyperlipidaemia for cardiovascular disease, serum lipid and glucose level should be closely monitored in diabetes. Chronic Hyperglycaemia resulting from diabetes has profound effects on nearly every system of the body. The toxic effect...
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REGULATORY CHALLENGES IN GLOBAL PHARMACEUTICAL MARKET
The global pharmaceutical industry “looks like the epitome of a modern, mature industry that has found a comfortable way to make profits by the billion: it’s global, hi-tech, and has the ultimate customer, the health care budget of the world’s richest countries. A number of factors contributed to the globalization of the pharmaceutical industry. Chief among these are the convergence of medic...
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AQUEOUS ROOT EXTRACT OF THE ANTIMALARIAL HERBAL CRYPTOLEPIS SANGUINOLENTA (LINDL.) SCHLTR DELAYS THE DEVELOPMENT OF PHYSICAL LANDMARKS AND SENSORIMOTOR SYSTEMS IN MICE
We demonstrated previously that the aqueous root extract of Cryptolepis sanguinolenta (cryptolepis), with cryptolepine as the major constituent adversely affect reproduction and foetal development in mice. However, very little is known on the effect of prenatal exposure of cryptolepis on the post-natal life of surviving animals. Using murine models, we report here, the effects of prenatal exposu...
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CREATININE CLEARANCE AS A MARKER FOR DIAGNOSING THE SEVERITY OF PREECLEMPSIA
Background: For many years, creatinine clearance has become increasingly popular because of several advantages. The major error arises in clearance test when the timing of urine collection is inaccurate and the bladder is incompletely empty. Aim: In view of the aforementioned controversial literature, it was decided to evaluate the relation-ship between the renal changes (creatinine clearance) ...
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TESTING EFFICACY OF HERBAL DRUG “FORTEGE” IN TREATMENT OF METAL INDUCED INFERTILITY IN MALE MICE
Fertility was tested in 0.5 mM/kg b. wt. (i.p) Lanthanum chloride exposed mice. Beneficial effects of “Fortege” an ayurvedic medicine (Alarsin co. Bombay) were also tested. Lanthanum chloride affected sperm count and motility. Lanthanum chloride could have affected Sertoli cells adversely and that have reduced sperm’s ability of uptake of fructose and as a result of it sperms became unable t...
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IMPACT OF SODIUM AND POTASSIUM IONS IN IDENTIFICATION OF OFFSPRING GENDER IN HAMSTERS
Impacts of sodium and potassium in diet to determine offspring gender in hamsters have been investigated. Sex determination has scientific basis for prevention of genetic diseases in addition to social backgrounds.20 healthy hamsters chosen from the first generation of the previous experimental hamsters, were divided in to two groups in the hamsters male to female 1:5. The first group was Na and...
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