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ISOLATION AND IDENTIFICATION OF ANTIBIOTIC PRODUCING MICROORGANISMS FROM SOIL
Antibiotics are most important commercially used secondary metabolites, produced by many soil microorganisms i.e., bacteria and fungi and employed in wide range. Most important antibiotics used today are of microbial origin. The emergence of the antibiotic resistance and need of broad spectrum antibiotics is in focus and in demand. In present study, soil samples from different areas were collected...
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COMPARATIVE PHARMACEUTICAL QUALITY CONTROL TESTING OF DIFFERENT BRANDS OF PARACETAMOL TABLETS AVAILABLE IN THE TRINIDAD & TOBAGO, WEST INDIES
Paracetamol tablets are popular over the counter (OTC) products among the patients as a good analgesics and antipyretics. The objective of this study was to compare the quality of the paracetamol tablet formulations those are locally available in Trinidad & Tobago pharmaceutical market manufactured by various pharmaceutical companies with pharmacopoeia standards. The four popular brands (A, B,...
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A REVIEW ON ACTINOMYCETES AND THEIR BIOTECHNOLOGICAL APPLICATION
Recent findings from culture-dependent and culture independent methods have demonstrated that indigenous marine actinomycetes exist in the oceans and are widely distributed in different marine ecosystems. There is tremendous diversity and novelty among the marine actinomycetes present in marine environments. Progress has been made to isolate novel actinomycetes from samples collected at different ...
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REVIEW ARTICLE ON PERMEATION ENHANCERS: A MAJOR BREAKTHROUGH IN DRUG DELIVERY TECHNOLOGY
The human skin serves as an impediment, a thermo regulator and prevents excessive loss of water from the internal organs. Various ways of transferring the drugs have been developed by modifying the barrier properties of the skin. Enhancement in skin penetration by hydration of the stratum corneum, or by use of chemical enhancers acting on the lipids and keratinized structures in the stratum corneu...
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A REVIEW OF PELLETS AND PELLETIZATION PROCESS – A MULTIPARTICULATE DRUG DELIVERY SYSTEM
Multiparticulate drug delivery systems like pellets, granules, micro particles, minitablets etc., prove to be promising and highly flexible systems with ease of formulating with different drug release kinetics. These multiparticulate dosage forms are essential where drug-excipients or drug-drug physicochemical interactions are possible in a single-unit formulation. In present times, pelletization ...
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MICROBIAL PIGMENTS AS A NATURAL COLOR: A REVIEW
Natural pigments have great interest with in the market now a day’s particularly microbial pigments. The various microorganisms such as Micrococcus, Bacillus, Rhodotorula, Monascus, Phaffia, Sarcina and Achromobacter have the capability to produce different pigments. These colors have number of beneficial properties like anti-cancerous, immunosuppressive, antibiotic, anti-proliferative, bio-degr...
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TINOSPORA CORDIFOLIA: A PHYTOPHARMACOLOGICAL REVIEW
Plants have been one of the important sources of medicines since the beginning of human civilization. There is a growing demand for plant based medicines, health products, pharmaceuticals, food supplements, cosmetics etc. A review of chemical constituents present in various parts of Tinospora cordifolia and their pharmacological actions is given in the present article. Tinospora cordifolia, is a c...
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RUBIA CORDIFOLIA – A REVIEW ON PHARMACONOSY AND PHYTOCHEMISTRY
Herbs & its formulations have a long history of use in the treatment of human diseases. Herbal extracts have long been regarded as a source of new and useful pharmaceuticals. According to Cragg's investigation, approximately 62 % of commercially available drugs have natural product origins. Manjistha, or Rubia Cordifolia to give it its scientific name, is a branched climber with small, green...
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A REVIEW ON BETEL LEAF (PAN)
The World Health Organization adopted a major policy change in accepting that most developing nations would have to make use of more traditional medical practices for primary health care. Piper betel L.belongs to family Piperaceae commonly known as Pan. It is extensively grown in Sri Lanka, India, Thailand, Taiwan and other Southeast Asian countries. This oil may be used as an industrial raw mater...
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TECHNOLOGY TRANSFER IN PHARMACEUTICAL INDUSTRY: TRANSFER OF PROCESS FROM DEVELOPMENT TO COMMERCIALIZATION
Appropriate technology transfer is both integral and critical to drug discovery and development for new medicinal products and is also important to upgrade drug quality designed during research and development and to final product during manufacturing as well as to assure stable quality transferred. Successful development and commercialization of innovative technologies is always fraught with diff...
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