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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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Most Cited

CITATIONS REPORT: (Source- Google Scholar)
 
Year 202020212022Total
No. of Published Articles 745760548 2053
Citations 69926321 983
Projected Impact Factor 3.7620.64  
Total Citations: 48275
 
Title
Views
PDF
Cited
47.

PREVALENCE OF HIV INFECTION IN EAST REGION OF INDIA

AIDS is syndrome of a set of disease, which is caused by HIV I and II. These viruses mainly destroy the lymphocytes which play a major role in our body immune system. Till now, there is not taken exactly prevention on this virus. Although some antiviral drugs are produced which make a preventive barrier out of the lymphocytes cells of patient’s blood but there is no way to kill the virus properl...

Shreyasri Dutta*, Pradip Kumar Mondal and Srima Adhakari

Microbiology Department, Gurukul Kangri University (KGC), Jwalapur, Haridwar- 249404, Uttarakhand, India

DOI:

2794-2798

2905

948

50.

IN SILICO DRUG DOCKING OF PHYTO INHIBITORS AGAINST TRIOSEPHOSPHATE ISOMERASE IN PLASMODIUM FALCIPARUM

Malaria caused by the parasite Plasmodium falciparum is a major public health concern. The parasite lacks a functional Tricarboxylic acid cycle (TCA), making glycolysis its sole energy source. One such enzyme is triose phosphate isomerase. This catalyzes the isomerization of D-Glyceraldehyde 3 phosphate to dihydroxy acetone phosphate. An attempt was made to identify the potential phyto inhibitor...

Pramod Shinde*, Vijay S. Savakare, Devangi Sarang and Komal Patil

Department of Bioinformatics, Guru Nanak Khalsa College, Matunga, Mumbai-400019, Maharashtra,India

DOI: 10.13040/IJPSR.0975-8232.4(7).2812-16

2812-2816

5005

1249

12.

IDENTIFICATION OF POTENT VIRTUAL LEADS AS TOPOISOMERASE-II INHIBITORS USING PHARMACOPHORE MODELLING, MOLECULAR DOCKING AND ADME STUDIES

Topoisomerase enzymes are highly expressed in cells which undergo rapid multiplication. Inhibition of this enzyme represents a potential therapeutic approach for diseases such as cancer. In order to understand the structure activity correlation of 2, 4, 6 pyridine based topoisomerase inhibitor, we have carried out a combined pharmacophore modelling, 3D-QSAR studies, molecular docking and virtual s...

Sanal Dev and Sunil R. Dhaneshwar*

Faculty of pharmacy- university of Aleppo. Department of analytical and food chemistry, Syria

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(8).2939-54

2939-2954

3213

1278

14.

STUDYING OMEGA-3 AND OMEGA-6 CONTENT OF NATIVE WALNUT AND STORAGE EFFECT ON IT

Walnuts from Northwest region of Syria was collected to determine Omega-6   (linoleic acid (LA, 18:2n-6)) and Omega-3 (α-linolenic acid (ALA, 18:3n-3)) in their oils, also called essential fatty acids (EFAs). This work was carried out using two different portions of samples. First samples were collected at harvest and second samples stored for one year under normal conditions. The extraction of...

Warid Khayata*, Nazira Sarkis and Abdulnasser Mohamed Ali

Department of Analytical and Food Chemistry, Faculty of Pharmacy, University of Aleppo, Syrian Arab Republic

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(8).2963-66

2963-2966

3016

1091

23.

SIMULTANEOUS QUANTITATION AND VALIDATION OF PHENYLEPHRINE HYDRO-CHLORIDE, AMBROXOL HYDROCHLORIDE AND LEVOCITRIZINE HYDROCHLORIDE IN SYRUP FORMULATION BY REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY

A simple, precise and accurate RP-HPLC method was developed and validated for the estimation of Phenylephrine hydrochloride, Ambroxol hydrochloride and Levocetirizine hydrochloride in syrup formulation. This method is based on HPLC separation of the three drugs on Octadecyl Silane C18 column (250 mm × 4.6 mm, 5.0μ), with isocratic conditions and mobile phase containing 0.01M Sodium dihydrogen ph...

Padmakana Malakar*, Arup Ratan Deb and S. K. Veliyath

Department of Pharmaceutical Chemistry, Azad College of pharmacy, Moinabad, R.R. District, Hyderabad , Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(8).3028-38

3028-3038

3186

1178

28.

FORMULATION AND EVALUATION OF FLOATING MATRIX TABLETS OF METFORMIN HCl FOR THE TREATMENT OF TYPE-2 DIABETES MELLITUS

Floating matrix tablets of Metformin hydrochloride were developed and evaluated to increase bioavailability by increasing gastric residence time and sustained release of drug in the upper part of gastrointestinal tract thereby diminishing side effects and enhanced patient compliance. The tablets were formulated by using central composite design having two independent variables at three levels. Ind...

Ishab Kumar*,Gali Vidyasagar , Anil Bhandari and Nishant Upadhyay

Department of Pharmaceutical Sciences, Jodhpur National University, Narnadi, Jhanwar Road, Jodhpur, Rajasthan, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(8).3065-72

3065-3072

3188

1234

35.

SYSTEMATIC FORMULATION DEVELOPMENT OF IMMEDIATE RELEASE TABLET DOSAGE FORM USING QUALITY BY DESIGN APPROACH

The main goal of this study was to develop a stable formulation of model antibacterial drug as an immediate- release tablet systematically using Quality by Design approach of which design of experiments is an integral part. The model drug was found to be a BCS class II drug official in USP having a plasma half-life of three to four hours. The formulation development work was initiated with wet gra...

Namrata Saxena* and Birendra Shrivastava

Mylan laboratories Limited, Plot No. 34A, Anrich Industrial Estate, Bollaram, Jinnaram Mandal, Medak district, Andhra Pradesh, India

DOI: : http://dx.doi.org/10.13040/IJPSR.0975-8232.4(8).3110-24

3110-3124

4236

2055

38.

LEAD FINDING FROM WHOLE PLANT OF CURCUMA LONGA WITH OXIDATIVE POTENTIAL

The present study deals with the antioxidant activity, drug likeness score and bioactivity score of the compounds isolated from Curcuma longa and search lead antioxidant compound through molinspiration software.  We have taken ten compounds from this plant. All the compounds were further subjected to molecular properties prediction and drug likeness by Molinspirstion and found in compliance with ...

Sadhana Singh*, Ashok Kumar Gupta , Amit Chattree and Amita Verma

Department of Chemistry, Sam Higginbottom Institute of Agriculture, Technology and Sciences- Deemed University, Allahabad, Uttar Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(8).3142-46

3142-3146

2607

1137

44.

LINEAR RESPONSE APPROXIMATION (LRA) APPROACHES FOR CALCULATING BINDING AFFINITIES OF QUINAZOLINE ANALOGUES AS ALK5 INHIBITORS

Quinazoline and its analogues have important therapeutic value in the treatment of cancer to induce apoptosis in cancer cells in a proliferation-independent manner. The binding free energies of quinazoline based inhibitors of kinase were computed using linear interaction energy method with a surface generalized Born (SGB) continuum solvation model in the human ALK5 kinase domain. A training set of...

Md. Afroz Alam*, Thalitha Jane Davina and Anurupa Devi

Assistant Professor (SG), Department of Bioinformatics, Karunya University, Karunya Nagar, Coimbatore, 641114, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(2).583-95

583-595

2915

1212

47.

EFFECT OF TRIGONELLA FOENUM GRAECUM ON LACTATE DEHYDROGENASE (LDH) ACTIVITY OF BLOOD, LIVER AND PANCREAS IN NORMAL AND ALLOXAN- INDUCED DIABETIC MICE

The effect of aqueous seeds extract of Trigonella foenum graecumLinn was studied on Lactate dehydrogenase (LDH) activity of blood, liver and pancreas in normal and alloxan- induced diabetic mice. Our study showed that aqueous seeds extract, Oral administration of 50 mg/animal (0.5 ml of extract) in alternative days up to 7 days (1st, 3rd, 5th & 7th day). In alloxan induced diabetic mice, there...

Dharmaseelan Sarasa , Sekaran Sridhar* and Egambaram Prabakaran

Department of Botany, Govt. Arts College, Thiruvannamalai 606 603, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(2).605-09

605-609

2697

1203