Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 3.76 | 2 | 0.64 |
DOCKING, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL QUINOLINE CONTAINING SCHIFF BASES FOR ANTI-INFLAMMATORY AND ANTI-OXIDANT ACTIVITIES
Quinolines bears a very good synthon so that a variety of novel heterocyclic with good pharmaceutical profile can be designed. There are various biological activities for quinolones such as antibacterial, antimalarial and various drugs possessing quinolone as nucleus are ciprofloxacin (Cipro), lomefloxacin (Maxaquin), norfloxacin (Noroxin), ofloxacin (Floxin), moxifloxacin (Avelox) and levofloxaci...
2035
904
ESTIMATION OF TOTAL FLAVONOIDAL CONTENT AND NOOTROPIC ACTIVITY OF LEPIDIUM SATIVUM
Objective: Lepidium sativum (Garden cress) is traditionally an important plant with a wide range of activities from the ages. Ample literature about its biological activities, motivate us to evaluate the total flavonoids content and to screen the nootropic activity in mice. Methods: Ethanolic extract was prepared from the seeds of Lepidium sativum using ethanol (70% v/v) and total flavonoids conte...
1504
626
BIOMOLECULAR CHANGES DUE TO STREPTOCOCCUS MUTANS INFECTION AND ANTIBIOTICS TREATMENT IN THE HUMAN DENTAL CARIES – SILKWORM (BOMBYX MORI) DISEASE MODEL
Changes in the hemolymph protein and trehalose contents of the silkworm, Bombyx mori L. due to Streptococcus mutans infection and antibiotics treatment was evaluated. Interestingly, S. mutans, which was successfully grown in the body of the larvae led to decline 69.60 and 50.21% of protein content in the hemolymph. Concomitantly, there was a drastic rise in the content of trehalose to 60.22 and 65...
1396
670
SYNTHESIS, IDENTIFICATION OF IN-SILICO INTERACTIONS AND BIOLOGICAL STUDIES OF NOVEL SCHIFF BASE LIGAND AND ITS COPPER (II) COMPLEX
A novel copper (II) complex has been synthesized with Schiff base ligand obtained by the reaction of substituted carbohydrazone and thiosemicarbazide hydrochloride from the condensation reaction of ester and primary aromatic amine. The synthesized ligand and its copper (II) complex were characterized by various spectroscopic techniques like FT-IR, H1 NMR, UV-Visible, Fluorescence, powder XRD and T...
1503
700
EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF COLEUS VETTIVEROIDES ROOTS ON EXPERIMENTALLY INDUCED HEPATO TOXIC MODELS
The present study was aimed to assess the hepatoprotective activity of ethanolic extract of Coleus vettiveroides on experimentally induced hepatotoxic models. Phytochemical screening of EECV was carried out and the results showed the presence of carbohydrates, alkaloids, tannin, flavonoids, phenolics, proteins and aminoacid, steroids and triterpenoids. HPTLC screening of EECV was carried out along...
1447
668
DEVELOPMENT AND CHARACTERIZATION OF POLYMERIC MICROPARTICLES CONTAINING MURRAYA KOENIGII LEAVES EXTRACT FOR MANAGEMENT OF DIABETES MELLITUS
Objective: Formulation and development of polymeric microparticles containing murrayanol for better treatment of diabetes mellitus. Methods: Successive solvent extraction of leaves of Murraya koenigii plant was done. The active constituent of leaves that is murrayanol was isolated and identified through HPLC and FTIR. Polymeric microparticles were selected as a carrier system and formulated by the...
1379
643
THE EFFECT OF GOAT MILK CONSUMPTION ON BLOOD CALCIUM AND HEMOGLOBIN IN SOCCER PLAYERS
Calcium and iron are the main minerals needed to support performance and also to improve the physical components of soccer players. This study aims to analyze the effect of goat milk consumption on calcium and blood hemoglobin levels in junior soccer players. This study was an experimental study with a pretest-posttest design. Research subjects were 22 soccer players, male, aged 12-14 years. The t...
1889
650
STABILITY INDICATING UHPLC METHOD FOR SIMULTANEOUS ESTIMATION OF SOFOSBUVIR AND LEDIPASVIR IN TABLET DOSAGE FORM
A stability-indicating UHPLC method was developed for the simultaneous estimation of Sofosbuvir (SOF) and Ledipasvir (LPS) in bulk and tablet dosage form. The study was performed using C18 BEH column (210 mm × 50 mm, 1.7 µm), with a mobile phase consisting of acetonitrile (55% v/v) and phosphate buffer of pH 3 (45% v/v) at a flow rate of 0.3 ml/min. The detection was carried at 247 nm using PDA ...
1937
617
IN-VIVO ANTIHYPERLIPIDEMIC ACTIVITY AND PRELIMINARY PHYTOCHEMICAL SCREENING OF BAUHINIA ACUMINATA
The global burden of CVD is rising due to its increasing prevalence in lower- and middle-income countries where 80% of all global CVD-related deaths occur. Common significant risk factors for dyslipidemia included obesity, diabetes, and dysglycemia. The present study was aimed to investigate the potential antihyperlipidemic activity of ethanolic leaf extract of Bauhinia acuminata in atherogenic di...
1509
815
ANTIBIOTIC SUSCEPTIBILITY PATTERN OF ESBL PRODUCING BACTERIA FROM URINARY TRACT INFECTION (UTI)
Antibiotics inhibit bacterial cell wall synthesis, protein synthesis or nucleic acid replication. The antibiotic must have access to and bind to its bacterial target site. Whether antibiotic resistance is intrinsic or acquired, the genetic determinants of resistance encode specific biochemical resistance mechanism that may include enzymatic inactivation of the drug, alteration to the structure of ...
4031
1239