Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.87 | 4.57 | 2.15 | 1.07 | 0.58 | 0.38 |
IN-SILICO DESIGN, SYNTHESIS AND CHARACTERIZATION OF NOVEL COUMARIN DERIVATIVES AS EGFR INHIBITORS
In the search for novel anticancer drugs, coumarin derived chalcones were analysed using in-silico tools like chemdraw, chemsketch, molinspiration, CASTp, Argus lab etc. Epidermal growth factor receptor protein is involved in cell signaling pathways that control cell division and survival. Molecular docking studies of test compounds with the EGFR tyrosine kinase domain (PDB ID: 6LUD) protein provi...
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PERCEPTION ABOUT HEALTH STATUS, SELF MEDICATION PRACTICE AND QUALITY OF LIFE OF ADOLESCENTS IN WEST TRIPURA: A CROSS-SECTIONAL STUDY
Background: The study has been carried out to assess the perception health status, self-medication practice and quality of life of adolescents in West Tripura and to find out the factors affecting them. Methods: A cross-sectional study has been carried out in West Tripura district. The students of all the schools of randomly selected sub-division were the study population. For data collection, SF-...
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COMPARATIVE STUDY OF OXIDATION OF L-CYSTEINE AND DL- METHIONINE BY POTASSIUM PERMANGANATE IN ALKALINE MEDIUM
Kinetics of oxidation of L-cysteine and DL- Methionine by potassium permanganate in alkaline medium was studied spectro-photometrically at room temperatue. The reaction was found to be of first order with respect to amino acid, zero order with respect to oxidant and fractional order dependence on Alkali. It was found that the rate of the reaction increases with increase in concentration of [OH-]. ...
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EVALUATION OF ERRORS AND COMPLETENESS OF RESEARCH APPLICATION FORMS SUBMITTED TO THE INSTITUTIONAL ETHICS COMMITTEE (IEC) OF A TERTIARY CARE INSTITUTION: AN OBSERVATIONAL STUDY
Introduction: IECs seek a duly filled application form to provide the overview of the study as per ICMR guidelines in the process of review and to maintain study related records. Aim and Objectives: To evaluate the errors and completeness of research application forms submitted to IEC. Materials and Methods: The present study was undertaken after obtaining approval from IEC, GMC, Kathua. Applicati...
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GC-MS/MS: A TARGETED QUANTIFICATION OF POTENTIAL NITROSAMINE IMPURITIES IN APIXABAN
The detection and quantification of nitrosamine impurities in pharmaceutical products are critical due to their potential carcinogenicity. This study presents the development of a sensitive Gas Chromatography-Mass Spectrometry (GC-MS) method for the analysis of nitrosamine impurities in Apixaban drug substance. The method demonstrates high specificity, sensitivity, and compliance with regulatory g...
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A RETROSPECTIVE STUDY ON THE PATTERNS OF CERVICAL PAP SMEAR FINDINGS IN DIABETIC AND NON-DIABETIC WOMEN AT A TERTIARY CARE HOSPITAL
Introduction: Carcinoma cervix is one of the most common cancers accountings for 15% of all the cancers diagnosed in women. Diabetes mellitus is considered a main factor that increases the propensity to get genital infections, especially when uncontrolled. This analysis allowed us to identify an intriguing pattern that opens up new avenues for investigation. Aims and Objectives: To study the PAP s...
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CANCER CHEMOTHERAPY-INDUCED CACHEXIA: THE ORPHAN DISEASE
Cancer remains a major cause of mortality worldwide, with chemotherapy serving as a cornerstone of cancer treatment. While effective in targeting malignant cells, chemotherapy is associated with debilitating side effects, including cachexia a complex, multifactorial syndrome characterized by unintentional weight loss, muscle wasting, fatigue, and reduced physical function. This condition arises fr...
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A NOVEL ANTIOXIDANT-DAPAGLIFLOZIN COMBINATION: COMBATING DIABETIC KIDNEY DISEASE AT THE CELLULAR LEVEL
At present, the significant cause of chronic kidney disease (CKD) is said to be Diabetic Kidney Disease (DKD). This condition considerably impacts cost of healthcare, mortality and morbidity worldwide. Current treatment options for DKD basically focusses on Blood Pressure (BP) regulation, glycemic control along with suppression of Renin-Angiotensin-Aldosterone System (RAAS). The advancing nature o...
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RECENT ADVANCEMENT IN THE DEVELOPMENT OF THERAPEUTIC PEPTIDES
Peptides are naturally occurring biologics, which provide essential functions as hormones, growth factors, biological messengers, anti-infective, neurotransmitters, and antimicrobials. Peptide hormones such as insulin, vasopressin, oxytocin, and gonadotropin-releasing hormone have significantly accelerated advances in modern drug development fields, including biology, chemistry, pharmacology, and ...
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ANUPDATED CLINICAL REVIEW OF ABNORMAL VAGINAL DISCHARGE AND REPRODUCTIVE TRACT INFECTION
Vaginal discharge is the commonest symptom reported in reproductive tract infection the recognition and diagnosis of the correct cause of abnormal vaginal discharge (AVD) can be challenging due to the wide spectrum of infectious agents. Reproductive tracts infections (RTIs) can cause serious physical and psychological harm, and this harm is not limited only to the women themselves, but also a seri...
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