A COMPARATIVE AND CORRELATIVE STUDY BETWEEN BLOOD AND SALIVARY GLUCOSE WITH BLOOD HbA1c IN TYPE 2 DIABETESAbstract
Diabetes is a non-communicable disease characterized by increased blood glucose. As regular monitoring of glucose and glycated hemoglobin (HbA1c) levels in diabetic individual’s blood causes psychological stress, development of a non-invasive technique to quantify glucose and HbA1c are essential. This study was carried out to compare and correlate the blood and salivary glucose and blood HbA1c levels in diabetic individuals. Results showed that mean blood and saliva glucose levels were higher in the uncontrolled diabetic group than controlled diabetic and control groups. Blood HbA1c level was also elevated in uncontrolled type-2 diabetes (T2D) group, followed by controlled diabetic and control groups. A significant difference was noticed between the blood and saliva glucose levels of control and uncontrolled T2D groups. Further, the difference in serum HbA1C levels between control, controlled T2D, and uncontrolled T2D groups was also significant. Taken together, these results explicated the use of saliva as a non-invasive, painless technique in the management of T2D patients.
S. Harish and M. Shantaram *
Department of Studies and Research in Biochemistry, Mangalore University, Post Graduate Centre, Jnana Kaveri, Chikka Aluvara Kodagu, Karnataka, India.
01 May 2018
12 July 2018
18 July 2018
01 January 2019