19.
Background: The current study used computational approaches to investigate the molecular, physicochemical and drug-like properties of some 4-(10-acetyl-10H-phenothiazines-3-yl)-1-phenylazetidin-2-one derivatives. Methods: The structures of the compounds were drawn using Chemdraw ultra12 and smiles were generated using ACD chem sketch software. The physicochemical and molecular properties were calc...
Sandip Sen *, Bairam Ravindar, Sirikonda Jala and Laxmi Dharabonia
Department of Pharmaceutical Chemistry, School of Pharmacy, Gurunanak Institute Technical Campus, Ibrahimpattnam, Telangana, India.
DOI: 10.13040/IJPSR.0975-8232.13(8).3163-73
3163-3173
20.
The present research is intended for the formulation development, optimization, and in-vitro evaluation of bi-layer tablets containing Enalapril maleate, hydrochlorothiazide in the immediate release layer and Nifedipine in the sustained release layer based on GEMINEX technology. The impact of formulation variables such as combination of polymers and coating solution on the drug release was evaluat...
Srinivasarao Jagarlamudi * and Gopinath Chakka
Department of Pharmaceutical Science, Guntur, Andhra Pradesh, India.
DOI: 10.13040/IJPSR.0975-8232.13(8).3174-86
3174-3186
21.
Present study reported a simple, rapid, eco-friendly and economical method for efficient production of AgNPs utilizing Manilkara zapota (M. zapota) extract. UV-Vis spectroscopic analysis was employedto ascertain the formation and stability of the synthesized AgNPs. The AgNPs were further characterized using TEM (Transmission Electron Microscopy), DLS, FT-IR, and XRD. The AgNPs exhibited a clear SP...
Sonia Parashar and Munish Garg *
Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, Haryana, India.
DOI: 10.13040/IJPSR.0975-8232.13(8).3187-93
3187-3193
22.
Background: Pain is a common symptom having huge public health importance. Conventional analgesics relieve pain effectively but cause various unwanted side effects. Hence the search for a novel analgesic with favourable risk-benefit profile is essential. Objectives: The current study was undertaken to investigate the analgesic activity of the ethanolic, hexane and chloroform extracts of sesame see...
K. Dayana and M. R. Manasa *
Department of Pharmacology, Karwar Institute of Medical Sciences, Karwar, Karnataka, India.
DOI: 10.13040/IJPSR.0975-8232.13(8).3194-98
3194-3198
23.
Diarrhea alters the movement of ions and water that follows an osmotic gradient and leads to Loose, watery stools, abdominal cramps, abdominal pain, fever, bloating, blood, and mucus in the stool. Numerous critical cases have been observed in both infants and adults. The main objective of this study is based on an exploration of risk factors of diarrheal infection caused in neonates by entering pa...
S. Pal, K. K. Mishra, D. C. Sharma and D. K. Sharma *
Department of Microbiology, Mewar University, Mewar, Rajasthan, India.
DOI: 10.13040/IJPSR.0975-8232.13(8).3199-07
3199-3207