13.
Ipomoea shupangensis (Kasunungure) is used by traditional healers in Gokwe, Zimbabwe for diabetic foot ulcers (DFUs), which are frequently complicated by multidrug-resistant (MDR) pathogens. Scientific validation of its phytochemistry, pharmacological activity, and safety was previously lacking. This study integrated an ethnopharmacological survey (40 healers), maceration extraction (five solvents...
M. Mubaiwa *, T. Manyarara and J. Chifamba
Department of Pharmacy and Pharmaceutical Sciences, Faculty of Medicine and Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
DOI: 10.13040/IJPSR.0975-8232.17(11).3443-60
3443-3460
14.
Introduction & Objective: Chronic stress activates the HPA axis and the sympathetic nervous system, leading to inflammation and oxidative toxic stress (OTS). Conventional therapies face bottlenecks like high costs, limited accessibility, and side effects. This study evaluates the chemical safety and metabolomics of Zimbabwean Withania somnifera. Methodology: Dried Withania somnifera roots were...
A. Tagwireyi and J. Chifamba *
Department of Pharmacy and Pharmaceutical Sciences, Faculty of Medicine and Health Sciences, University of Zimbabwe, P. O. Box MP167, Mt Pleasant, Harare, Zimbabwe.
DOI: 10.13040/IJPSR.0975-8232.17(11).3461-72
3461-3472
15.
Novel effective delivery systems for chemotherapeutic drugs are of utmost demand in nanomedicine. Herein, we prepared magnetite (Fe₃O₄) nanoparticles (NPs) coated with either low molecular (LM) or high molecular (HM) weight Chitosan or Carboxymethyl Chitosan (CMC) and assessed their drug loading and release efficiencies. Chitosan/CMC-coated MNPs were fully characterized by various physiochemic...
Johar K. Al Khalifah, O. M. Lemine, Alia Mustafa, Khaled Greish and Kheireddine El-Boubbou *
Department of Chemistry, College of Science, University of Bahrain, Sakhir 32038, Bahrain.
DOI: 10.13040/IJPSR.0975-8232.17(11).3473-88
3473-3488
16.
Introduction: Burkea africana Hook, a medicinal plant in the family Fabaceae, subfamily Caesalpinioideae, is a medium-sized, woody, deciduous tree widely used in traditional medicine. It is used to treat conditions such as pain, inflammation, bacterial infections, gastrointestinal disorders, and reproductive problems. Despite its extensive traditional use, there is limited scientific evidence supp...
B. G. Muzamwese* and J. Chifamba
Department of Pharmacy and Pharmaceutical Sciences, Faculty of Medicine and Health Sciences, University of Zimbabwe, P. O. Box MP167, Mt Pleasant, Harare, Zimbabwe.
DOI: 10.13040/IJPSR.0975-8232.17(11).3489-97
3489-3497
17.
Leonurus japonicus Houtt. (Lamiaceae), commonly known as Chinese motherwort or Yi-Mu-Cao, has a longstanding history in traditional Asian medicine. This study comparatively evaluated the phytochemical constituents, antioxidant capacity, anti-acne properties, and in-vitro anti-inflammatory activities of hot-water extracts obtained from the aerial parts and roots of L.japonicus cultivated in Norther...
Nakornsub Lawcharoen, L. E. Kanyaphat, Sutthikiat Udommethaporn and Alinthipat Kanchaburin*
School of Integrative, Mae Fah Luang University, 333 Moo1 Thasud, Mueang, Chiangrai 57100, Thailand.
DOI: 10.13040/IJPSR.0975-8232.17(11).3498-05
3498-3505