Non-alcoholic fatty liver disease (NAFLD), a common chronic liver condition, is high in developed nations. One of the factors leading to chronic liver disease and cryptogenic cirrhosis has been identified as NAFLD. Multiple risk factors, including obesity, insulin resistance, diabetes mellitus, hyperlipidemia, and hypertension-related cardiovascular disease, contribute to the development of NAFLD....
Autism spectrum disorders (ASDs) refer to the group of neuropsychiatric disorders that alter neurodevelopment and mental function and are characterised by an extensive range of symptoms, including hyper-or hyposensitivity, repetitive behaviours, and impairments in social and academic functioning. Untangling the causation of ASD has been complicated, in part because distinct genetic abnormalities ...
Immunotherapy is among cancer immunology's fastest and most furious treatment strategies. The therapeutic perspective of checkpoint inhibitors is represented through the Food and Drug Administration (FDA) approvals for their implementation in various malignancies. Efforts to improve results with immunotherapeutic agents have led to the design of advanced treatment strategies. Current pre-clinical ...
With a threshold of 3 DSM-1, rice is one of the crops that are most sensitive to salt. Salinity in agricultural areas is primarily brought on by the overuse of irrigation water that is overly salty. The early vegetative and seedling stages of rice are the most vulnerable to salt stress, followed by the reproductive phases. When osmotic stress inhibits root water uptake, too much salt in the soil h...
Lead comes in a category of toxic heavy metal which acts as a pollutant when present in high concentration in the environment and cause severe effects on the human body. Due to its continuous use its level increases and serves as a serious threat for the society. Lungs and skin are the first organs which get affected by Lead toxicity. Lungs are the most important and sensitive part of human ther...
The present study is aimed to compare the in-vitro antibacterial and antioxidant activities of Aralia cordata Thunberg and Kalopanax septemlobus (Thunb.) Koidzumi (Araliaceae). The antibacterial activity of the two plants was evaluated disc diffusion and minimal inhibition concentration (MIC) method against two Gram-positive bacteria and two Gram-negative bacteria. The tested ether and ethyl aceta...
Multiple anatomical and physiological obstacles have always made ocular drug administration difficult. Different novel drug delivery systems, including nanogels, nanoparticles, liposomes, dendrimers, implants, contact lenses, nanosuspensions, microneedles, and in situ thermosensitive gels, have been developed to get around the barriers to improve ocular Bioavailability. For the encapsulation of vi...
The plant Pinda concanensis belongs to family apiaceae. It was native to the Western Ghats of India, but it is now becoming rare as a result of widespread usage of the seeds for their therapeutic properties. It is an annual herb with tuberous roots, which are eaten raw by local folklore. Apiaceae is the well-known aromatic plant family having beneficial uses in home remedies, abundance of phytoche...
Introduction: Endothelial dysfunction and diet-induced diabetes may be significantly impacted by changes in Adipokine and inflammatory cytokine secretion linked to obesity. Our study's objective was to determine the effect of a high-fat diet also on concentrations of leptin, adiponectin, as well as other inflammatory indicators in type 2 diabetes mellitus brought on by streptozotocin (STZ)-induced...
Polycystic ovarian syndrome (PCOS) known by its name can be correlated with Soothaga Vaayu in Siddha classical literature which is one of the most common forms of metabolic and endocrine disorders of women, with a high prevalence among the reproductive age group, often associated with obesity, hypertension, insulin resistance, diabetes mellitus, hyperinsulinemia and dyslipidemia. Current therapeut...