1.
The liver is the most important organ in the body that plays a central role in the detoxification and excretion of many exogenous and endogenous compounds. Due to these functions, hepatic diseases continue to be among the main threats to public health, and that challenges health care professionals. Many liver diseases are chronic, meaning they last for years and may never go away. But even chronic...
Krishn Kumar Agrawal and Yogesh Murti *
Institute of Pharmaceutical Research, GLA University, Mathura, Uttar Pradesh, India
DOI: 10.13040/IJPSR.0975-8232.12(9).4549-79
4549-4579
2.
The noble coronavirus SARS-CoV-2 results in a devastating, multisystem disease among which COVID-19 pneumonia creates serious complications and most of COVID-19 related deaths. COVID-19 patients develop a systemic inflammatory response through interleukin (IL) and tumor necrosis factors. In COVID-19 patients, cytokine storm controlling is the key step for treatment because cytokine attacks own bod...
N. P. Neupane, A. Adhikari, S. Alok, A. K. Singh and A. Verma *
Bioorganic and Medicinal Chemistry Research Laboratory, Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, U. P, India.
DOI: 10.13040/IJPSR.0975-8232.12(9).4580-87
4580-4587
3.
Covid-19, caused by Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) is a life-threatening disease that has been declared a global pandemic. Even with the intervention of numerous medical systems to combat Covid-19, an effective remedy is not yet in sight rather than supportive therapies accompanied with anti-viral drugs and vaccines. The usage of these medicines has caused for unexpe...
J. I. D. Diddeniya and P. K. Perera *
Institute of Indigenous Medicine, University of Colombo, Colombo, Sri Lanka.
DOI: 10.13040/IJPSR.0975-8232.12(9).4588-99
4588-4599
4.
Excessive drug therapy, environmental pollutants, hepatic cancer and alcoholic intoxicants are the main causes of liver disorders. The hepatic disorders/toxicity can occur by several mechanisms like cytochrome P450 activation, lipid peroxidation, induction of nitric acid synthase, mitochondrial dysfunction, activation of pro-inflammatory mediators and bile acid-indu...
Varsha Raj *, Prevesh Kumar, Munish Mani and Navneet Verma
Department of Pharmacy, I. F. T. M. University, Moradabad, Uttar Pradesh, India.
DOI: 10.13040/IJPSR.0975-8232.12(9).4600-15
4600-4615
5.
Periodontitis is a destructive inflammatory disease of the periodontium induced by specific microorganisms and requires more specific treatment. The traditional mechanical therapy alone is not sufficient for the treatment of moderate to severe periodontitis because of in accessibility in the deep periodontal pocket and depth of penetration of microorganisms into the periodontal connective tissues....
Raju Anarthe *, Preeti Kale, Amit Mani and Shriram Kendre
Department of Periodontology, Rural Dental College of Pravara Institute of Medical Sciences- DU Ahmednagar Loni , Maharashtra, India.
DOI: 10.13040/IJPSR.0975-8232.12(9).4616-25
4616-4625
