11.
Ursolic acid is a pentacyclic triterpenoid widely distributed in medicinal plants and is recognized for a broad spectrum of biological activities, including antioxidant and antidiabetic effects. In the present study, leaves of Eucalyptus tereticornis Sm. were subjected to sequential solvent extraction, and ursolic acid was isolated by column chromatographic purification. Structure of the isolated ...
Shiwa Chaubey, Manjoosha Srivastava * and Nisheeth Rastogi
Phytochemistry Division, CSIR–National Botanical Research Institute, Lucknow, Uttar Pradesh, India.
DOI: 10.13040/IJPSR.0975-8232.17(8).2365-81
2365-2381
12.
For many generations in Zimbabwe, Albizia antunesiana tree has been used in traditional healing. It has been widely used to treat infections, inflammation and other chronic illnesses such as diabetes. This study sought to provide scientific evidence to this ancient wisdom by testing the bark and leaves against modern biological markers. Phytochemical analysis revealed the presence of bioactive com...
Nicholas Muparadzi *, Joey Chifamba and Shingirayi Zengeni
Department of Pharmacy and Pharmaceutical Sciences, Faculty of Medicine and Health Sciences, University of Zimbabwe, P. O. Box MP167, Mt Pleasant, Harare, Zimbabwe.
DOI: 10.13040/IJPSR.0975-8232.17(8).2382-95
2382-2395
13.
Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia resulting from impaired insulin secretion, insulin action, or both, leading to serious long-term complications. Glibenclamide, a widely used sulfonylurea antidiabetic drug, is effective in stimulating insulin secretion; however, its therapeutic performance can be influenced by pharmacokinetic variability an...
P. S. Malathy, Chikram Vigneshwar and Y. Narasimha Reddy *
Department of Pharmacology, University College of Pharmaceutical Sciences, Kakatiya University, Warangal, Telangana, India.
DOI: 10.13040/IJPSR.0975-8232.17(8).2396-04
2396-2404
14.
Huntington's disease is a progressive neurological condition characterized by motor dysfunction, cognitive decline, and psychiatric disturbances. Recent studies indicate that abnormalities in DNA mismatch repair mechanisms, particularly involving the MSH3 protein, contribute to the expansion of CAG repeats and the progression of the disease. In the current investigation, an integrated in-silico st...
Adela Melari Lyngdoh, Amthul Saboora, Jedidiah Serena Abraham, Afreen Reesha, G. Gayathri, Rakshana Santosh G, Erumalla Venkatanagaraju
Department of Life Sciences, Indian Academy Degree College (Autonomous), Hennur Cross, Bengaluru, Karnataka, India.
DOI: 10.13040/IJPSR.0975-8232.17(8).2405-14
2405-2414
15.
The standardization of Siddha formulations is a critical step for establishing consistent chemical profiles and ensuring quality control in the commercial manufacturing of herbal drugs. Vilvathy Legium is a Siddha polyherbal formulation in the Siddha Sastric textbook, Athmarakshamirtham Ennum Vaidhiya Sarasangiragam, authored by Kandhasamy Mudhaliyar and indicated for conditions such as gastrointe...
A. Divya *, V. Priyadharshini, P. Arul Mozhi and M. Meenakshisundaram
Department of Kuzhandhai Maruthuvam, National Institute of Siddha, The Tamil Nadu Dr. M.G.R Medical University, Chennai, Tamil Nadu, India.
DOI: 10.13040/IJPSR.0975-8232.17(8).2415-26
2415-2426