A CRITICAL REVIEW ON COLON TARGETED DRUG DELIVERY SYSTEMS FOR MANAGEMENT OF INFLAMMATORY BOWEL DISEASEAbstract
Inflammatory bowel disease (IBD) refers to the inflammation of the colon and small intestine of the body, in which Crohn’s disease and ulcerative colitis are the principal types of IBD. This article covers most of the information related to a drug delivery system for treatment regarding intestinal diseases more emphasized to inflammatory bowel diseases. Currently, using delivery systems for targeting drugs to colon are osmotic drug delivery system, chronotropic system, pulsinicap system, multiparticulate system, port system, COLAL-Pred system, gas empowered drug delivery system have included in this article. An approach for targeting drugs to the colon is a probiotic approach has also included in this article. These delivery systems are being used to improve the bioavailability of the poorly absorbed drug. The purpose of this review article is to study about techniques employed in colon targeting for the prevention and treatment of IBD.
M. Jaiswal * and S. K. Lanjhiyana
Institute of Pharmaceutical Sciences Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, India.
14 July 2018
29 September 2018
05 October 2018
01 March 2019