A REVIEW ON NOVEL APPROACH TO PHARMACEUTICAL DRUG DELIVERY: 3D PRINTINGAbstract
To develop a standard conventional solid dosage form like tablets it include the operations involving like milling, mixing, granulation, drying and compression which able to result in different qualities of the final products concerning the loading of the drug, the release of the drug, stability of the drug and pharmaceutical dosage form stability. To overcome some challenges of conventional pharmaceutical unit operations, 3DP is gaining more attention in the pharmaceutical formulation in the future. 3DP can successfully overcome the issues relating to the drug delivery of peptides, potent drugs, water-soluble drugs, and the release of multi-drugs, etc. The ideal opportunity of this technology is the preparation of personalized doses to state individual patient needs. This technology can be seen as the future of solid dosage forms produced on demand, with lower in cost and it also helps in minimizing side effects caused by excessive doses. However, some problems that limit the applications of 3DP in the commercial market, such as selections of binders which are suitable and excipients and the pharmacopeial properties of finishing products. Here, we present an outline and the perspective of 3DP in the development of novel drug delivery systems.
A. E. Kumar *, G. C. Devi and N. Sharada
Department of Pharmaceutics, University College of Pharmaceutical Sciences, Palamuru University, Mahabubnagar, Telangana, India.
26 July 2018
15 October 2018
16 October 2018
01 April 2019