A STUDY ON PARAMOUNTCY OF COGNITIVE PHARMACEUTICAL CARE IN DRUG-DRUG INTERACTION AMONG INPATIENTSAbstract
Drug-drug interactions (DDIs) are known for their potential to cause adverse clinical outcomes, rate of morbidity and mortality. An integrated approach to cognitive pharmaceutical care (CPS) would decrease the incidence of DDIs in hospitalized patients. This prospective interventional study was carried out among the inpatients admitted to a tertiary care multispecialty hospital in Chennai. A total of 749 drugs were accumulated from 100 in-patients. A perpetual continuous quality improvement (CQI) program was conducted to edify and train the healthcare staff on a weekly basis with counter-current data collection on DDIs. The results 645 DDIs in which 153 (23.72%) were major, 348 (53.95%) were moderate and 144 (22.32%) were minor. The CPS recommendations like dose adjustment, time of drug administration, alternate drug choice etc. were incorporated into the DDIs. The post CQI results depicted a gradual decrease in the prevalence of DDIs for a period of 3 months. This study revealed the pertinence of CPS in the management of potential DDIs. The need for structured, as well as integrated approaches guidelines, also was recommended.
M. Bothiraj *, M. Alagusundaram and K. B. C. Sekhar
Jawaharlal Nehru Technological University, Ananthapuramu, Andhra Pradesh, India.
28 February 2019
20 December 2019
26 December 2019
01 January 2020