A SURVEY ON ANTICANCER PROPERTIES OF INDIAN MEDICINAL PLANTS – A BROAD SPECTRUM ANALYSISAbstract
Several plants across the world possess specific therapeutic and diagnostic properties. The identification of the properties among them is the most difficult task. Several researchers have used several methodologies to express the therapeutic properties in the plants. The interest of scientists among the anticancer studies has been increasing widely as cancer has become one of the deadliest diseases. The usage of different parts of the plant and using the different extracting solvents has shown effective results on different types of cancer cell lines. Several plants synthesize metabolites which possess anticancer properties that have been used in the development of drugs by clinical trials. The application of nanoparticles from plants in cancer treatment has been regarded as a successful method recently. The present review aims at the study of a broad spectrum of plants having anticancer properties using the in-vitro analysis of particular cell lines. The anticancer activity was analyzed by different assays such as MTT assay, “Alamar Blue” Resazurin reduction assay, SRB assay, and WST-1 assay. The results were calculated based on absorbance values. Thus, the potential of the plant extract against specific cancer cell line was evaluated.
K. Saranya, V. Manivasagan, R. Kanakadurga, V. P. M. Babu * and N. G. R. Babu
Department of Biotechnology, Adhiyamaan College of Engineering (Autonomous), Hosur, Tamil Nadu, India.
15 November 2018
17 February 2019
28 February 2019
01 August 2019