ALZHEIMER’S DISEASE: A CHALLENGE IN MANAGING WITH CERTAIN MEDICINAL PLANTS – A REVIEWAbstract
It is well known that some plants have medicinal properties and their knowledge has been accumulated in the course of many centuries, based on different medicinal systems such as Ayurveda, Unani and Siddha. In India, it is reported that traditional healers use nearly 2,500 plant species and 100 plant species serve as regular sources of medicine for the treatment of various diseases. Alzheimer’s disease is globally recognized as the most common form of dementia and it disrupts critical metabolic processes which keep neurons healthy. These disruptions cause nerve cells in the brain to stop working, lose connections with other nerve cells and finally die. The destruction and death of nerve cell causes the memory failure, personality changes and problems in carrying out daily activities. The Alzheimer’s disease has an abundance of two abnormal structures- amyloid plaques and neurofibrillary tangle. The Alzheimer’s disease is caused by a mixture of genetic, environmental, and life style factors. The current review methodically summarizes the Alzheimer’s disease and the effects of phyto-chemicals of medicinal plants in various models of Alzheimer’s disease.
G. K. Pratap, S. Ashwini and M. Shantaram*
Department of Studies in Biochemistry, Mangalore University, Chikka Aluvara, Karnataka, India.
19 March, 2017
13 October, 2017
12 November, 2017
01 December, 2017