AN OVERVIEW OF BACTERIOPHAGE THERAPY OVER ANTIBIOTICS; AS AN ALTERNATIVE FOR CONTROLLING BACTERIAL INFECTIONSAbstract
Lung cancer is a malevolent lung growth characterized by unrestrained cell expansion in tissues of the lung. EGFR is occupied dissimilar fundamental presentation of cancer cells that includes expansion of cells, enlargement, propagation, apoptosis regulation etc. make it a prime objective for lung cancer. EGFR is a tyrosine kinase inhibitor that is proposed in epithelial cells. EGFR inhibitors are drugs that connect to firm parts of EGFR and stop the expansion of cells. Till date, EGFR inhibitors are classified into two categories first one is tyrosine kinase inhibitor and the second one is monoclonal antibodies. Tyrosine kinase inhibitor binds to the area of tyrosine kinase in the epidermal growth factor receptor and hinders the activity of EGFR. Monoclonal antibodies bind to the extracellular components of EGFR prevent it to bind with its own receptor so that stop cell division. This review encompasses complete updates on a generation of epidermal growth factor receptor tyrosine kinase inhibitor used in the treatment of non-small cell lung cancer.
P. Joshi, A. Singh * and D. Bisht
Department of Pharmaceutical Sciences, Bhimtal Campus Bhimtal, Kumaun University Nainital, Uttarakhand, India.
08 June 2019
15 October 2019
03 February 2020
01 March 2020