AN OVERVIEW ON BUCCAL DRUG DELIVERY SYSTEMAbstract
Buccal drug delivery has gained significant attention and momentum since it offers remarkable advantages. Over past few decades, buccal route for systemic drug delivery using mucoadhesive polymers to significantly improve the performance of many drugs has been of profound interest. This review article is an overview of buccal drug delivery systems encompassing a review of oral mucosa, formulation considerations for buccal drug delivery system, theories and mechanism of mucoadhesion, different mucoadhesive formulations for buccal drug delivery and active ingredients delivered via the buccal route. Additionally, commercial technologies and future prospects of this route of drug delivery are discussed.
Surender Verma, Mahima Kaul*, Aruna Rawat and Sapna Saini
Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra, Haryana, India
11 March, 2011
11 April, 2011
16 May, 2011
01 June, 2011