ANTICOCCIDIAL AND ANTIOXIDANT ACTIVITY OF GASTRO’IMMUNE -POLYHERBAL FORMULATION ON COCCI OOCYSTS INFECTED MICE JEJUNUMAbstract
Herbal drugs are prescribed widely as an anti-coccidial agent even when their biologically active compounds are unknown, because of their effectiveness, lesser side effects, and relatively low cost. So, in the current study, a poly-herbal formulation was used to find out its effect as an anti-coccidial effect. In the present study, the parameters evaluated were the WBC count, Glutathione levels, malondialdehyde (MDA) levels, and the in-vitro nitric oxide radical scavenging activity. All the altered parameters significantly brought back to normal by the administration of the polyherbal formulation in comparison to the standard drug Co-trimoxazole (20 mg/kg p.o.)The histopathology of the jejunum further revealed the healing effects of the polyherbal formulation in Eimeria papillata induced coccidiosis.
S. Ghosh, R. Sinharay, N. Bangodi, K. P. S. Gowda *, N. Loganayaki, S. Kumar and K. Venkateswarlu
Department of Pharmacology, PES College of Pharmacy, Bengaluru, Karnataka, India.
22 May 2018
29 October 2018
03 November 2018
01 February, 2019