ANTIMICROBIAL, CYTOTOXICTY AND ANTI CANCER ACTIVITY OF SILVER NANOPARTICLES FROM GLYCYRRHIZA GLABRAAbstract
In this study, the plant Glycyrrhiza glabra was explored for the synthesis of silver nanoparticles (SNPs). The SNPs were characterised by ultra-violet-visible spectroscopy, FTIR analysis and scanning electron microscopy. SEM analysis revealed the formation of SNPs of average size of 46 nm with aqueous extract of G. glabra. The SNPs synthesised by aqueous extract of G. glabra showed strong antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa and significant inhibition to other bacteria and few fungi tested. The SNPs also exhibited potential anti cancer activity. The SNPs was observed to be nontoxic from a concentration of 500 µg/ml in vero cell line. The results document SNPs can be synthesised using aqueous plant extracts for applications in the biomedical field.
N. Pandian and Soundhari Chidambaram *
Department of Microbiology, Valliammal College for Women, Chennai, Tamilnadu, India.
11 September, 2016
13 January, 2017
20 March, 2017
01 April, 2017