ANTIOXIDANT PROPERTIES OF POLYGALA CHINENSIS L. WHOLE PLANT ON ALLOXAN INDUCED DIABETIC RATSAbstract
Administration of ethanol extract of Polygala chinensis whole plant (100 mg/kg and 200 mg/kg body weight) to alloxan induced diabetic rats for 14 days reduced the elevated level of lipid peroxidation (LPO). The treatment also resulted in significant increase in reduced glutathione (GSH), glutathione peroxidase (GPx), superoxide dismutase (SOD) and catalase (CAT) in serum, liver and kidney. The results confirm the antioxidant activity of P. chinensis whole plant and suggest that because of its antioxidant effects its administration may be useful in controlling the diabetic complications in experimental diabetic rats.
K. Rajalakshmi and V.R. Mohan*
Ethnopharmacology Unit, Research Department of Botany, V. O. Chidambaram College, Tuticorin, Tamil Nadu, India
26 September, 2012
29 October, 2012
22 December, 2012
01 January, 2013