ANTIPYRETIC AND ANALGESIC ACTIVITY OF PICRORHIZA KURROOA RHIZOMESAbstract
Picrorhiza kurroa Royle ex Benth, belongs to the family Scrophulariaceae has gained immense medicinal value in Ayurvedic as well as in modern medicines including antioxidant, anti-inflammatory, anti-pyretic, immunomodulatory, anticancer, hepato-protective, etc. The present study aimed to ascertain analgesic and antipyretic activities of rhizome extracts of Picrorhiza kurrooa in Wister rats. Methanolic extracts at 260 mg/kg as well as 520 mg/kg exhibited highly significant (P<0.01) analgesic and antipyretic activity by oral dose for analgesic and rectal dose for antipyretic effects. Whereas hydroalcoholic extract showed significant effects at 520 mg/kg but not as good as that of methanolic extracts.