BIOEFFICACY OF PREMNA CORYMBOSA ROTTL. (VERBANACEAE) WITH SPECIAL REFERENCE TO ITS ANTIOXIDANT ACTIVITYAbstract
In the present investigation, the bioefficacy of an indigenous plant was investigated with special reference to its antioxidant potential. Antioxidant effects of Methanolic, Chloroform and Ethyl acetate extracts of the leaves of Premna corymbosa Rottl. (family Verbenaceae) were tested based on DPPH (1, 1-diphenyl-2-picryl-hydrazyl), phosphomolybdenium assay, superoxide radical scavenging activity, and metal chelating activity. Results about the present investigation indicate that the methanol extract of the P. corymbosa showed strong antioxidant activities than the other solvent extracts. This study has made it clear that Premna corymbosa is an effective antioxidant. Such extracts could be more widely used in developing countries for the prevention and treatment of cancer. These extracts may be considered as good sources for drug discovery.
A. Manimaran *, M. M. J. J. Cruz, S. Subha and P. Arumugam
Department of Biotechnology , Aarupadai Veedu Institute of Technology, Vinayaka Mission University, Paiyanoor, Chennai, Tamil Nadu, India.
27 February 2014
23 April 2014
23 May 2014