CHITIN, CHITOSAN AND THEIR PHARMACOLOGICAL ACTIVITIES: A REVIEWAbstract
Chitin is the second most important natural amino polysaccharide polymer after cellulose in the world. The main sources exploited are marine crustaceans, shrimp, and crab apart from that some other lobstera, insects, sulphur butter and fungi. Chitosan is the most important natural based common cationic polymer got from chitin has gotten developing consideration for the most part due to their bio-degradable, bio-compatible, bio-renewable and non-lethal properties. The deacetylated chitin derivative chitosan is a useful and interesting bioactive polymer; it has a large pharmaceutical application either. It has numerous reactive amino side groups, which offer possibilities of chemical modifications, formation of a large variety of beneficial derivatives. Chitosan has been found to be used as a support material for pharmaceutical application, gene delivery, cell culture, and tissue engineering. This review is based on the various pharmacological activity of chitosan such as wound healing, anti-hypertensive, anti-cancer, blood coagulant, anti-coagulant, anti-ulcer, anti-microbial, anti-viral, hypolipidemic and hypocholesterolemic etc.
K. Tripathi and A. Singh *
Department of Pharmaceutical Sciences, Kumaun University, Nainital, Uttarakhand, India.
15 November, 2017
16 February, 2018
04 March, 2018
01 July, 2018