COMPARATIVE ANTI-ANXIETY POTENTIAL OF DIFFERENT PARTS OF VITEX NEGUNDO LINN.Abstract
Vitex negundo, commonly called Nirgundi, is one of the widely investigated medicinal plants of India. The present study were planned to compare different parts, i.e. leaves, stems and roots of V. negundo for antianxiety activity using elevated plus maze model. Petroleum ether (60 – 80 °C), chloroform, ethanol and aqueous extracts of these parts were prepared and evaluated for anti-anxiety activity. Among the different parts compared, only the roots showed significant anti-anxiety activity. Chloroform (400 mg/kg) and ethanol (100 mg/kg) extracts of the roots showed maximum significant anti-anxiety activity, compared to that of diazepam (2 mg/kg).
A. Sharma, Gulsheen, A. Kumar* and A. Sharma
University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, Punjab, India.
05 May, 2017
24 October, 2017
17 November, 2017
01 January, 2018