DENTAL CARIES AND LACTOBACILLUS: ROLE AND ECOLOGY IN THE ORAL CAVITYAbstract
Dental caries is an infective serious transmittable bacterial disease characterized by a multi-factorial pathology. Main players in the etiology of this disease are cariogenic bacteria, fermentable carbohydrates, a susceptible tooth, the host, and the time. It is still one of the most common disease worldwide. Biological factor such as cariogenic bacteria plays an important role in dental caries initiation, progression as well as tooth decay. Previous studies suggested that the main pathogenic bacteria are Streptococcus mutans and Lactobacillus. Consequently, Lactobacillus is considered the second most cariogenic bacteria of oral flora. It is not the caries initiator but plays an important role in caries progression. Most of the previous studies were quantitative, so till now, researchers not know about the specific species of Lactobacillus which are directly associated with dental caries progression. Some species-level identification studies suggested that the most common Lactobacillus species are L. gasseeri, L. fermentum, L. vaginalis and L. casei which were predominantly reported at the most of the oral sites, i.e. saliva, tongue, carious lesion, dental plaque, etc. and maybe plays the main role in caries progression. The present review spotlights the role, pathogenicity of Lactobacillus in dental caries and their ecology in the oral cavity.
S. S. Ahirwar, M. K. Gupta and S. K. Snehi *
Department of Microbiology, Barkatullah University, Bhopal, Madhya Pradesh, India.
23 February 2019
07 June 2019
14 July 2019
01 November 2019