EVALUATION OF AEGLE MARMELOS FRUIT MUCILAGE FOR BINDING PROPERTIESAbstract
Plant products served as an alternative to synthetic products because of local accessibility, eco friendly nature and lower prices. Natural gums and mucilages are widely explored as pharmaceutical excipients. The present study was undertaken to separate mucilage from unripe fruits of Aegle marmelos (L) Corr. and explore its use as binder in tablets. The binding properties at different concentrations of mucilage were evaluated using Paracetamol as model drug. Mucilage at 3%w/w was found to be comparable with 10%w/w of starch paste. The drug release studies indicated that Aegle marmelos mucilage could be considered as a potential binding agent.
N. Gaikar and P. Sandhya
Department of Pharmacognosy, Saraswathi Vidya Bhavan’s College of Pharmacy, Dombivli (E), Dist-Thane, Maharashtra, India
12 September, 2011
11 January, 2012
29 January, 2012