EVALUATION OF PHYTOCHEMICAL, ANTIOXDATIVE AND ANTIMICROBIAL EFFECT OF MAGNIFERA INDICA, LEAF EXTRACTS ON ORAL DENTAL PATHOGENSAbstract
A major part of the total population in developing countries still uses traditional folk medicine obtained from plant resources. Chemical substances used for prevention of dental caries are known to have many side-effects. Thus, natural products should be explored for their anticaries action. Present study evaluate the antimicrobial effect of alcoholic and aqueous extracts of Magnifera indica leaves against oral dental pathogens Streptococcus mutans, Staphylococcus aureus. Ethanolic extract was found to be more effective and dose dependent against both pathogens. Phytochemical and antioxidative study was also performed using various methods of testing on the aqueous and ethanolic extracts for the presence of phenols, alkaloids, saponins, terpenoids, flavonoids, tannins and reducing sugar. Both leaf extracts showed higher anti oxidative capacity and phytochemicals content like alkaloids and steroids which are active antimicrobial components in plants. Present investigation provides preliminary information for using mango leaf extracts in the prevention of oral diseases such as dental caries.
Deepa Garg * and Nikhil Mohanan
School of Biotechnology and Bioinformatics, D. Y. Patil University, Navi Mumbai, Maharashtra, India.
17 September, 2016
30 November, 2016
02 December, 2016
01 April, 2017