IN-VITRO ANALYSIS OF CINNAMOMUM VERUM FOR FORMULATION OF BIO-ACTIVE COSMETIC GELAbstract
Plants have always been traditionally used to address various disorders. Due to their rich phytochemical profile, they have been employed in a gamut of skin care and concomitant treatment of disorders. In this Study, we screened the aqueous (CAE), hydroalcoholic (CHE) and ethanolic (CEE) extract of leaves of Cinnamomum verum for its activities The antioxidant potential of the extracts were determined by the DPPH (2,2-diphenyl-1-picrylhydrazyl) and FRAP (Ferric Reducing Antioxidant Potential) assays. The extracts showed good activity with increasing concentration. Further, extracts were screened for anti-Inflammatory property by HRBC membrane stabilization assay and Inhibition of Protein Denaturation. The results of anti-inflammatory activity were compared with standard control values. CHE was found to exhibit better activities as compared to the other two extracts and was subsequently screened for Tyrosinase inhibition, Elastase inhibition and Hyaluronidase inhibition activity. CHE showed moderate anti-inflammatory and Hyaluronidase-inhibition activity. CHE can therefore be used as a potential bioactive component in skin care products.
P. Dhawal, K. Satardekar *, S. Hariharan and S. Barve
KET's Scientific Research Center, V.G Vaze College Campus, Mulund, Mumbai, Maharashtra, India.
30 December, 2016
15 February, 2017
17 February, 2017
01 July, 2017