IONTOPHORESIS: AN APPROACH TO DRUG DELIVERY ENHANCEMENTAbstract
The skin has been used as a medium for systemic delivery of therapeutic agents. The resistance provided by the stratum corneum is the major barrier in delivering of the agents through skin. Due to this the number of drug molecules used under this category is limited. Iontophoresis is an efficient technique for physically enhancing conveyance of molecules across skin for local and systemic effects. The main feature offered by iontophoresis is the control offered by it in dose modulation by adjustment of current applied to undergo the process. It is suitable as an alternative for parenteral route as it is pain free and cost effective technique. The flux associated with iontophoretic treatment is described along with its applications in the article. The future aspects of iontophoretic treatment and the medications currently available are included in this article. Iontophoresis as a treatment regimen has gained popularity in relatively less treatment methodology but the concept should be well popularized as it offers enhancement to transdermal drug delivery system. This system being non invasive, pain free and with minimum side effects must be made use of in most of the treatment regimen.
S. Shahi * and S. Deshpande
SVKM’s NMIMS, School of Pharmacy & Technology Management, Shirpur Campus, MPTP, Babuldhe, Shirpur, Dhule, Maharashtra, India.
21 February, 2017
28 April, 2017
04 May, 2017
01 October, 2017