LC-MS ANALYSIS OF BIOLOGICALLY ACTIVE EXTRACTS FROM POLYHERBAL FORMULATION TO TREAT PSORIASISAbstract
The present study deals with the identification of the phytochemical compounds in ethanol, acetone and benzene extracts from polyherbal formulation composed of the bark of Ficus religiosa, the root of Smilax chinensis, seeds of Nigella sativa, the fruit of Emblica officinalis, Terminalia chebula and Terminalia bellerica which is used to treat psoriasis. The bioactive components of different extracts of the polyherbal formulation were determined by liquid chromatography coupled with mass spectroscopy (LC-MS) analysis. LC-MS analysis of the ethanol extract of the polyherbal formulation revealed the presence of the 9 bioactive chemical constituents, 5 phytochemicals in the acetone extract of polyherbal formulation and the benzene extract consist of 4 bioactive compounds. The results of this present study provide scientific support to medicinal uses of the polyherbal formulation. These compounds may exhibit an antipsoriatic activity which can be done in further studies.
S. Elavarasi *, H. I. Averal and C. Ignatius
PG and Research Department of Zoology, Holy Cross College (Autonomous), Tiruchirappalli, Tamil Nadu, India.
30 December 2018
29 March 2019
01 April 2019
01 September 2019