MACORVIS – A NEW OPPORTUNITY FOR ADDITION TO THE TREATMENT OF CARDIOVASCULAR DISEASESAbstract
Standartizated plants extracts are new opportunity in addition with standard therapy. Hawthorn extract, Tribulus terrestris extract and magnesium gluconate are forming well balanced nutritional supplement that could benefits people with cardiovascular diseases and diabetes. All three substances are well known in the common herbal medicine in our country and abroad. Their mechanisms’ of actions is pointed in this review. Some pilot studies suggest recommended dosages for all of the three substances. Side effects and drug interactions are also considered, because they are serious problem not only to the common drugs but in herbal medicines too. Interesting fact is that in mouse models the dose dependence vasodilatation from hawthorn is not impaired by common medicine like: Diphenydramine, Propranolol, Verapamil and Glibenclamide. Another issue that we consider pregnancy and risk from this three particular extracts. Many data has shown that use of this kind of supplementation could be dangerous for the mother and the child, and our device in first place is “primum non nocere”. Magnisium gluconate proven to be beneficial in combination with tribulus, and hawthorn extracts in people with different stages of heart failure and arrhythmias. Due to its hormone activity and the saponin protodioscin tribulus is used as a sex stimulant and herbal hormone substitution in women in menupause. All three substances manage to improve coronary blood flow (the most influences has hawthorn extract), improve symptoms of heart failure such as “fatigue” and “breathlessness” in people with stage I or II according to NYHA. In conclusion Macorvis preparation represents a felicitous combination of adiovant therapy and / or protection in humans predisposition to heart disease This dietary supplement offers additional benefits associated with favorable effects on sexual function and increased libido in both sexes.