MICROSPHERES AS CONTROLLED DRUG DELIVERY SYSTEM: AN UPDATED REVIEWAbstract
Oral modified or controlled dosage forms have always proven to be more effective alternative to conventional or immediate release dosage forms. Controlled or modified drug delivery systems offer numerous advantages of delivering a drug to the body in a précised manner with an aim to minimize its unwanted side effects and maximize its benefits. Targeted drug delivery systems target a particular site in the body to maximize the drug concentration in a specified tissue or organ of the body which improves therapeutic efficacy of the drug, decrease toxicity and with better patient compliance and convenience. In past few decades, microspheres have promised targeted or controlled delivery of drugs in the body which has proved to be better than the conventional drug delivery. Recently microspheres have been used to deliver drugs, vaccines, antibiotics and hormones in a controlled manner. The present study aims to review different aspects of the microparticulate drug delivery system along with types of microspheres, methods of preparation and different applications as targeted or controlled drug delivery system.
S. Saini, S. Kumar, M. Choudhary, Nitesh and V. Budhwar *
Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, Haryana, India.
13 August, 2017
15 October, 2017
20 October, 2017
01 May, 2018