PEPTIDOMIMETICS AS A CUTTING EDGE TOOL FOR ADVANCED HEALTHCAREAbstract
With exponential advancements in healthcare and pharmaceutical sciences, Peptidomimetics have emerged as essential tools in the designing and development of novel and improvised therapeutics. The peptidomimetic based drugs are designed with the aim of overcoming the shortcomings of natural peptides and proteins. Thus, peptidomimetic therapeutics possesses increased efficiency, stability and overall better pharmacokinetic properties. This review paper outlines the applications and the underlying principles of peptidomimetic based therapeutics in various diseases and issues related to healthcare. Recent advancements in the development of peptidomimetics for Cancer therapy, Renin inhibition, HIV drugs, Analgesics, anti microbials and anti viral drugs have been discussed. Additionally, the applications of peptidomimetics in anti oxidants, anti malarial drugs, blood filtration membranes and as fibrinogen antagonists have also been included.
A. Shah*, B. Barathi, A. Nair and C. Rajam
School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu, India.
19 April, 2017
03 July, 2017
25 July, 2017
01 December, 2017