PHYTOCHEMICAL SCREENING AND ANTIOXIDANT ACTIVITY OF AERIAL PART EXTRACTS OF CYCLEA PELTATAAbstract
In recent years, there is an increasing interest in finding antioxidant phytochemicals for the prevention and treatment of complex diseases like diabetes, cancer, and atherosclerosis, which are associated with excessive biological oxidative stress. Plants are rich source of natural antioxidants that inhibit the propagation of free radical reactions and protect the human body from degenerative diseases. For the present study, entire vine (aerial part) of Cyclea peltata was selected based on their extensive use in folk medicine and ayurvedic medicine to cure various ailments. Hexane, chloroform, ethyl acetate, methanol and water extracts of Cyclea peltata were subjected to various in-vitro antioxidant activity studies. In most of the antioxidant parameters, ethyl acetate and methanol extracts showed potent activity and chloroform extract showed minimum antioxidant activity. From these studies, it can be concluded that ethyl acetate and methanol extracts of Cyclea peltata could be used as a source of potent natural antioxidant that can be used in various plant-based drugs or formulations for the treatment of complex diseases caused due to excessive biological oxidative stress.
S. Jagadeepchandra, K. Mruthunjaya * and N. Lakshmidevi
Department of Pharmacognosy, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India.
01 March 2019
23 June 2019
14 July 2019
01 December 2019