PRESENT INVESTIGATIONS AND FUTURE PROSPECTS OF ORAL DISINTEGRATING TABLETS: A REVIEWAbstract
Oral Disintegrating Drug Delivery Systems (ODDDS) have the unique property of rapidly disintegrating and/or dissolving and releasing the drug as soon as they come in contact with saliva, thus obviating the requirement of water during administration. Methods to improve patient’s compliance have always attracted scientists towards the development of fancy oral drug delivery systems. Among them, oral disintegrating drug delivery systems (ODDDS) have acquired an important position in the market by overcoming previously encountered administration problems and contributing to extension of patient life, which includes dysphagic, bed ridden, psychic, geriatric and pediatric patients. This review describes the various technologies developed for ODTs, different patented technologies and their products, disintegrated employed and their mechanism of action, taste masking methods and evaluation tests.
Basani Gavaskar*, Subash Vijaya Kumar, Guru Sharan, Nagaraju M and Y Madhusudan Rao
Department of Pharmaceutics, Vaagdevi College of Pharmacy, Warangal (AP), India
24 April, 2010
19 June, 2010
02 August, 2010
15 August, 2010