PRONIOSOMES AS A DRUG CARRIER: A REVIEWAbstract
Nanotechnology is an advancing technology expected to bring revolutionary changes in the field of life sciences including drug delivery, diagnostics, nutraceuticals and biomedical for implants and prosthesis. The advance in nanotechnology helps in preparing newer formulations. One of the advancement in nanotechnology is the preparation of proniosomes. A comprehensive research has done on proniosomes as a drug carrier for transdermal delivery in last few years. Approaches to stabilize niosomal drug delivery system without affecting its properties of merits have resulted in the development of the promising drug carrier, proniosomes. Proniosomes is dry formulation using suitable carrier coated with non-ionic surfactants and can be converted into niosomes immediately before use by hydration. These proniosome derived niosomes are as good as or even better than conventional niosomes. The focus of this review is to bring out different aspects related to proniosomes preparation, characterization, entrapment efficiency, in vitro drug release, applications and merits.
Indira U and Uma Shankar M.S *
Department of Pharmaceutics, Krupanidhi College of Pharmacy, Sarjapura main road, Carmelaram post, Bangalore-560 035, Karnataka, India
21 August, 2012
04 October, 2012
20 November, 2012
01 December, 2012