SERUM CREATININE LEVEL IN HYPERTENSIVE PATIENTS: A STUDY FROM UTTARAKHAND, INDIAAbstract
Chronic Kidney diseases are increasingly recognized as a problem worldwide. Incidence of chronic kidney diseases is doubled in last fifteen years. The kidney is both cause and victim of hypertension. Hypertension is a serious risk factor for chronic kidney disease. The purpose of this study was to measure serum creatinine level in hypertensive patients as an indicator of kidney functioning and compared it with normal healthy controls. This study was carried out in Shanti Prapann Sharma Government Hospital, Rishikesh. In present study, the volunteers were selected from General Medicine department of Government hospital Rishikesh from May 2009 to May 2010. A total of 120 volunteers were recruited for this study. Out of them 70 were hypertensive subjects (38 males and 32 females) and 50 were normotensive subjects (27 males and 23 females). Hypertension was defined as per the recommendations of JNC7th Report. After 12 hours fast the blood samples were collected with the help of trained laboratory technician from all individuals without anticoagulant and centrifuged at 3000 rpm for 5 minutes. The serum was collected in fresh vial and standard method was followed for estimation of serum creatinine. The results conclude that the serum creatinine levels in hypertensive subjects were higher and statistically significant (p < 0.000).
Pooja* and Yashoda Mittal
Department of Zoology, Government Post Graduate College, Rishikesh, District – Dehradun, Uttarakhand, India
31 January, 2014
21 March, 2014
26 April, 2014
01 July, 2014