STUDIES ON WOUND HEALING ACTIVITY OF GEL FORMULATION CONTAINING COW GHEE AND ALOE VERAAbstract
The present study aims to evaluate the wound healing activity of gel containing cow ghee and aloe vera in rats. Incision wounds for tensile strength and excision wounds contraction along with the histopathological examination of the regenerated tissues were employed to investigate the wound healing potential. Topical application of the test formulation alone promoted the tensile strength (incision wounds) and wound contraction (excision wounds) showing healing potential comparable to framycetin sulphate cream (1%w/w). Histological examination reveals good keratinization, epithelization, fibrosis and collagenation indicative of the wound healing potential of gel. The present study thus offers a valuable insight into the claimed wound healing potential of the test formulation.
Rupali Nandanwar*, Himanshu Gurja, Vinod K. Sahu and Himanshu Saraf
Sri Rawatpura College of Pharmacy*, NH- 75, Kalapuram, Datia (M.P.)
12 January, 2010
22 February 2010
25 February, 2010
01 March, 2010