SURVEILLANCE AND ASSESSMENT OF ADVERSE DRUG REACTIONS AND COMPARISON WITH THE RETROSPECTIVE STUDIES IN A SECONDARY CARE HOSPITALAbstract
Adverse drug reactions are considered to be among the leading causes of morbidity and mortality. Approximately 5-25% of hospital admissions are due to ADR’s, and 6-15% of hospitalized patients experience serious adverse drug reactions (SADR’s), causing significant prolongation of hospital stay. The adverse drug reactions reported were classified based on Wills and Brown classification, Causality assessment by the Naranjo’s causality assessment scale, the severity of the adverse drug reactions was assessed using modified Hartwig and Siegel severity assessment Scale. Preventability of the adverse drug reactions was assessed using Schumock and Thornton preventability scale. A total of 108 suspected adverse drug reactions (ADR) were reported during the study period. Highest percentages of ADRs were seen in adults (62.03%) than geriatrics (24.07%) followed by pediatrics (13.89%). The present study concluded that continuous ADR monitoring Programme was found to be useful and beneficial in identifying the percentage of ADR occurrence on an annual basis in the hospital and also helpful to the patient and health care professionals for a better therapeutic outcome.
K. Moudgil, D. N. Chandu, A. Hamid and P. R. A. Vijayakumar *
Department of Pharmacy Practice, JSS College of Pharmacy, Ooty, Tamil Nadu, India.
12 November 2018
05 March 2019
16 March 2019
01 July 2019