SYNTHESIS, CHARACTERIZATION AND NUCLEASE ACTIVITY OF AU (III) – COMPLEXES OF BIACETYL MONOXIME THIOSEMICARBAZONE (BAMOT) AND SUBSTITUTED THIOSEMICARBAZONESAbstract
Metal complexes of Au(III) with Thiosemicarbazone and Substituted Thiosemicarbazones different thiosemicarbazones have been synthesized. The present communication reports the structural study of the Au(III) complexes with Biacetyl Monoxime Thiosemicarbazones and these complexes have been characterized by elemental analysis, conductance, IR, NMR and Mass spectral data. The physicochemical and spectral data suggests tetrahedrol geometry for various complexes. Metal complexes of Biacetyimonoxtme thiosemicarbazone (BAMOT) and Substituted Thiosemicarbazones are also investigated for better comparison. Au(III) complexes of Biacetyimonoxtme thiosemicarbazone (BAMOT) and Substituted Thiosemicarbazones are also investigated for better comparison. The ligand and metal chelates would be screened in vitro for anticancer activity against some cancer Cell lines.
Prakash MMS Kinthada and M. Adharvanachary*
Department of Complexity Science and Engineering, Division of Trans Disciplinary Science, University of Tokyo, Japan
18 July, 2011
24 August, 2011
01 November, 2011