THE NEWER DIMENSION OF INHALATION AEROSOLS IN THE PROSPECTIVE OF VALIDATIONAbstract
Aerosol drug delivery systems are much more importance in present days and have much advantage over other route of administration. Meter dose inhaler was used to deliver asthma medication in easy way and reliable multi dose preparation. The importance of the MDIs device play important role in determining drug delivery to the lungs. The word validation means,” Impose of validation or action of proving its effectiveness”. The most used inhalation is the metered-dose inhaler(MDI), which operates by delivering from a pressurized container using a liquefied gas propellant. Inhalation is the accessible way to deliver drugs to respiratory track and used in treatment of disease like ASTHMA.A manufacturer can assure that the design of the device, processes, process controls and packaging that all manufactured units will have to meet specifications and have uniform and consequent quality. Validation is defined as the collection and checking of data, from the process design stage throughout commercial production, which provides scientific evidence that a process is capable of consistently delivering quality product.
Sunil Kumar G. and M. P. Gowrav
Department of Pharmaceutics (Unit of Quality Assurance), J.S.S College of Pharmacy, J.S.S University, Sri Shivarathreeshwara Nagar, Mysore, Karnataka, India.
27 July, 2016
22 September, 2016
26 September, 2016
01 February, 2017