UROPATHOGEN RESISTANT ESSENTIAL OILS OF COLEUS AROMATICUS AND OCIMUM SANCTUMAbstract
Urinary tract infections are common type of pathogenic infections in body. Essential oils of Coleus aromaticus and two varieties of Ocimum sanctum (Rama Tulasi and Shyama Tulasi) were compared for antibacterial activity against urinary tract infection (UTI) causing bacteria; Staphylococcus aureus, Klebsiella oxytoca, Proteus vulgaris, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Proteus mirabilis. Ocimum sanctum (Rama Tulasi) and Coleus aromaticus oils showed remarkable activity, later being more active. Least activity was observed in Shyama Tulasi variety of Ocimum sanctum. Constituents of the oils were analyzed by GC-MS and GC-FID. The essential oils have promising inhibitory effect with minimal inhibitory concentration (MIC) ranging from 0.5μl/ml -6μl/ml. The essential oils of two varieties of Ocimum sanctum have differences both in chemical composition and MIC values against UTI infection causing pathogens.
Rashmi Sahay Khare Sourish Karmakar , Shanta Banerjee , Gopal Nath , Subir Kundu and Kanika Kundu*
Senior Associate Professor, Chemistry Section, MMV, Banaras Hindu University, Varanasi – 221005, Uttar Pradesh, India
02 May, 2011
21 May, 2011
25 July, 2011
01 August, 2011