WOUND HEALING ACTIVITY OF ETHANOLIC EXTRACT OF LUFFA ACUTANGULA (FRUIT)Abstract
The present study investigates the wound healing activity of ethanolic extract of the fruit of Luffa acutangula. The medicinal values of the Luffa acutangula have been mentioned ancient literature as useful in disorders of wound. Dried fruits of Luffa acutangula were powdered and extracted with ethanol using soxhlation method. Ethanolic extract of Luffa acutangula was evaluated for its wound healing activity in rats using excision wound model with help of Plethysmometer. Soframycin used as a standard drug. For this activity test groups received ethanolic fruit extract of Luffa acutangula. Results showed that in excision wound healing model, animals of standard treated and drug-treated (treated with ethanolic extract of Luffa acutangula) groups showed significant decrease in wound contraction ability, epithelialization period when compared to animals of normal control.
B. Verma, S. Dwivedi *, S. Raghuwanshi, N. Vyas, S. Malviya and A. Kharia
Department of Pharmacology, Modern Institute of Pharmaceutical Sciences, Indore, Madhya Pradesh, India.
30 October 2018
14 September 2019
24 September 2019
01 October 2019