EFFECT OF ADD ON THERAPY WITH OMEGA 3 FATTY ACIDS AMONG DIABETIC AND NON-DIABETIC DYSLIPIDEMIC PATIENTS ON RANDOM BLOOD GLUCOSE- A COMPARATIVE, RANDOMISED, OPEN LABEL, PROSPECTIVE STUDY
AbstractBackground: Diabetes is one of the leading non communicable disease-causing various health complications like Cerebrovascular accidents, micro and macrovascular complications. In Indian population, very few comparison studies have been conducted to evaluate the glucose lowering effect of omega 3 fatty acid between diabetic and non- diabetic dyslipidemic patients. Hence the present study was planned to compare the efficacy of omega 3 fatty acid among diabetic and non-diabetic dyslipemic individuals. Materials And Methods: This study is a comparative, randomized, open-label, prospective interventional study which compared the efficacy of omega 3 fatty acids as add on therapy among diabetic and non-diabetic Dyslipidemic patients.50 Patients of 25 each of diabetic dyslipidemia and non-diabetic dyslipidemia attending the out-patient department of Internal Medicine, Rajiv Gandhi Government General Hospital, Chennai were given 1 gram of omega 3 fatty acid- fish oil capsule per day once daily to take orally for 8 weeks and monitored for random blood glucose at baseline (0 weeks), after 4 weeks and after 8 weeks of treatment. Results: At 4 weeks and 8 weeks post intervention, RBS levels have drastically decreased in patients with diabetic dyslipidemia. (Group A) with P value of 0.0001 and 0.0001 respectively which are extremely statistically significant. Conclusion: Omega 3 fatty acids can be safely employed for use in Diabetes with Dyslipidemia.
Article Information
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758-764
824 KB
39
English
IJPSR
E. Hephzibah Magdalene *, K. M. Sudha and J. Joseph Jeremiah
Department of Pharmacology, Government Medical College Thiruvallur, Tamil Nadu, India.
maggimers@gmail.com
28 September 2024
01 November 2024
05 November 2024
10.13040/IJPSR.0975-8232.16(3).758-64
01 March 2025