URINARY DYNAMICS IN CHRONIC KIDNEY DISEASES
AbstractThis review explores the intricate physiology of urine formation and its critical relationship with chronic kidney disease (CKD). Urine formation involves three key processes: glomerular filtration, tubular reabsorption, and tubular secretion, which work together to maintain homeostasis by regulating fluid balance and waste elimination. In CKD, these functions are impaired due to progressive damage to the nephrons, leading to a reduced glomerular filtration rate (GFR) and accumulation of toxic metabolites, which contribute to a variety of complications including hypertension, electrolyte imbalance, and fluid overload. Understanding the mechanisms underlying urine production provides important insights into the pathophysiology of CKD and highlights the importance of early detection and treatment strategies. This review aims to highlight the importance of preserving renal function and improving treatment outcomes in patients with CKD by reviewing current research and clinical practice.
Article Information
4
1159-1168
684 KB
42
English
IJPSR
Aman Kumar, Akash Yadav * and Dinesh Kumar Jain
Indore Professional Studies Academy, College of Pharmacy, Indore, Madhya Pradesh, India.
akashyadav@ipsacademy.org
13 November 2024
09 December 2024
12 December 2024
10.13040/IJPSR.0975-8232.16(5).1159-68
01 May 2025
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