FILM-FORMING GELS: A PROMISING ALTERNATIVE FOR ENHANCED DERMAL AND TRANSDERMAL DRUG DELIVERY
AbstractA new method in this field called film-forming gels may offer an alternative to the common skin dosage forms such ointments, creams, gels, or patches. When applied as a liquid, the polymeric solution evaporates to create a nearly undetectable layer on the skin. Dermal medication delivery and transdermal drug delivery systems compared to traditional pharmaceutical dosage formulations, the approach can offer certain desirable performance, for eliminating first-pass metabolism in the stomach and liver, increasing medication bioavailability, lowering dosage frequency, and stabilizing drug delivery overview. The purpose of this review was to find alternatives to traditional forms that would decrease skin irritation, boost patient acceptability from a cosmetic standpoint, improve skin adhesion qualities, and enhance drug release. The unique rheological nature of polymeric gels makes them advantageous in terms of preparation simplicity. Application simplicity, adherence to the application surface, and broad drug delivery compatibility.
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